DISTINGUISHED CHARACTERISTICS OF INFECTIVE ENDOCARDITIS IN HIV/AIDS AMONG INTRAVENOUS DRUGS ABUSED
https://doi.org/10.17650/1818-8338-2011-3-19-22
Abstract
The aim – definition of distinguished characteristics of the right-sided infective endocarditis (IE) inintravenous drugs abused with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS).
Materials and methods. The study included 10 patients with right-sided IE in conjunction with HIV/AIDS. All patients were male, age – from 28
to 36 years.
Results. Course of the IE in HIV/AIDS among intravenous drugs abused in general corresponds to features specific to IE in intravenous drug users without HIV infection. Distinctive features of IE in these patients are a large burden of lung disease, its disseminated character, more tissue oxygenation disorders and marked pulmonary hypertension and haematological disorders (lymphopenia, anemia), and late diagnosis of IE.
Conclusion. Features of the current right-sided IE in intravenous drugs abused with HIV/AIDS are distinguished . Difficulties in diagnosis of IE in
HIV infection are due to variety of causes of prolonged fever, which should guide doctors to more frequent use of transthoracic echocardiography during prolonged fever in HIV-infected patients.
About the Authors
E. Y. PonomarevaRussian Federation
Department of Hospital Therapy, Medical Faculty
A. A. Roshchina
Russian Federation
Department of Hospital Therapy, Medical Faculty
A. P. Rebrov
Russian Federation
Department of Hospital Therapy, Medical Faculty
References
1. Гуревич М.А., Тазина С.Я. Особенности современного инфекционного эндокардита. Русский медицинский журнал 1998;6(16):1024–35.
2. Дёмин А.А., Дробышева В.П., Вельтер О.Ю. и др. Инфекционный эндокардит у «инъекционных наркоманов». Клиническая медицина 2000;(8):47–52.
3. Демин А.А., Демин Ал.А. Бактериальные эндокардиты. М., 1978.
4. Бартлетт Дж., Галант Дж. Клинические аспекты ВИЧ-инфекции. eBook, 2007. http://million-knig.ru/76288.html
5. Carrel T., Schaffner A., Pasic M., et al. Surgery of endocarditis in the drug dependent and HIV patient. A prospective comparison with conservative treatment. Helv Chir Acta 1993;60(3):439–45.
6. Habib G., Hoen B., Tornos P., et al.; ESC Committee for Practice Guidelines. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases
7. (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J 2009;30(19):2369–413.
8. Тюрин В.П. Инфекционный эндокардит с отрицательной гемокультурой: диагностика и лечение. Клиническая медицина 1997;(7):68–71.
9. Chan K., Currie P.J., Seward J.B., et al. Comparison of three Doppler ultrasound method in the prediction of pulmonary artery disease. J Am Coll Cardiol 1987;9:549–54.
10. Покровский В.В., Ермак Т.Н., Беляева В.В., Юрин О.Г. ВИЧ-инфекция: клиника, диагностика и лечение. М.: гэотарМед, 2003.
11. Филиппенко П.С., Драгоман Е.А. Инфекционный эндокардит у инъекционных наркоманов. Часть 2. Особенности клинической картины, диагностики и лечения. Клиническая медицина 2010;(2):22–9.
12. Утешев Д.Б., Карабиненко А.А., Филатова Е.Н., Сторожаков Г.И. Инфекционные и септические осложнения у наркоманов. Лечащий врач 2001;(1):28–31.
Review
For citations:
Ponomareva E.Y., Roshchina A.A., Rebrov A.P. DISTINGUISHED CHARACTERISTICS OF INFECTIVE ENDOCARDITIS IN HIV/AIDS AMONG INTRAVENOUS DRUGS ABUSED. The Clinician. 2011;5(3):19-22. (In Russ.) https://doi.org/10.17650/1818-8338-2011-3-19-22