ACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE DECOMPENSATED CHRONIC HEART FAILURE
https://doi.org/10.17650/1818-8338-2013-7-2-
Abstract
Objective: to estimate the frequency and magnitude of acute kidney injury (AKI) in patients with acute decompensated chronic heart failure
(ADCHF) and to clarify the relationship of AKI to mortality.
Subjects and methods. One hundred and four patients (58 men and 46 women; mean age 65.3 ± 10.68 years) with ADCHF were examined.
AKI was diagnosed and classified by the KDIGO criteria.
Results. In terms of creatinine, AKI was diagnosed in 74 (71 %) patients (Stage I in 51 (49 %), Stage II in 20 (19 %), and Stage III in 3 (3 %)
patients. Five (5 %) patients died during hospitalization. All the dead patients had AKI. Multivariate regression analysis demonstrated that regardless of gender, age, chronic heart failure stage, the in-hospital mortality was associated with the level of creatinine (R = 0.29; β = 0.20;
p = 0.046). At the same time, in the patients with AKI Stages II-III the probability of in-hospital mortality was higher than that in the other patients (relative risk, 23.4; 95 % confidence interval 2.9–187.0; p = 0.003).
Conclusion. More than half of the patients with ADCHF have AKI according to the KRIGO criteria. The in-hospital mortality is much higher
amongst the patients with AKI Stages II-III.
About the Authors
M. V. Menzorov
Ulyanovsk State University
Russian Federation
Russian Federation
A. M. Shutov
Ulyanovsk State University
Russian Federation
Russian Federation
E. R. Makeeva
Central City Clinical Hospital, Ulyanovsk
Russian Federation
Russian Federation
A. A. Strakhov
Central City Clinical Hospital, Ulyanovsk
Russian Federation
Russian Federation
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Review
For citations:
Menzorov M.V., Shutov A.M., Makeeva E.R., Strakhov A.A. ACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE DECOMPENSATED CHRONIC HEART FAILURE. The Clinician. 2013;7(2):29-33. (In Russ.) https://doi.org/10.17650/1818-8338-2013-7-2-
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