HYPERTENSION IN POSTMENOPAUSAL WOMEN: POSSIBILITIES OF COMBINATION THERAPY
https://doi.org/10.17650/1818-8338-2013-3-4-80-86
Abstract
Objective – to study the efficacy and safety of Tenoten in the combination therapy of hypertension in early postmenopausal women.
Subjects and methods. The study enrolled 60 early postmenopausal women with grade I–II hypertension. A study group included 30 women who took Tenoten during antihypertensive therapy (AHT); a control group comprised 30 women who received AHT only.
Results. Tenoten could achieve additional improvement of 24-hour blood pressure (BP) monitoring data in the postmenopausal hypertensive women. Tenoten was found to have a positive effect on general health, activity, and mood and to alleviate the symptoms of autonomic dysfunction and anxiety.
Conclusion. Tenoten that is able to alleviate the manifestations of anxiety and autonomic dysfunction, to exert a positive effect on blood
pressure values, and to improves health, mood, and social activity should be used in addition to AGT.
About the Authors
N. A. Shostak
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Acad. A.I. Nesterov Department of Faculty Therapy
Russian Federation
Acad. A.I. Nesterov Department of Faculty Therapy
N. G. Pravdyuk
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Acad. A.I. Nesterov Department of Faculty Therapy
Russian Federation
Acad. A.I. Nesterov Department of Faculty Therapy
D. A. Anichkov
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Acad. A.I. Nesterov Department of Faculty Therapy
Russian Federation
Acad. A.I. Nesterov Department of Faculty Therapy
A. A. Kondrashov
N. I. Pirogov Russian National Research Medical University, Ministry of Health of Russia
Russian Federation
Acad. A.I. Nesterov Department of Faculty Therapy
Russian Federation
Acad. A.I. Nesterov Department of Faculty Therapy
References
1. Chae C.U., Derby C.A. The menopausal transition and cardiovascular risk. Obstet Gynecol Clin North Am 2011;38(3):477–88.
2. Аничков Д.А., Шостак Н.А, Журавлева А.Д. Менопауза и сердечно-сосудистый риск. Рационал фармакотер в кардиол 2005;1(1):37–42.
3. Lima R., Wofford M., Reckelhoff J.F. Hypertension in postmenopausal women. Curr Hypertens Rep 2012;14(3):254–60.
4. Подзолков В.И., Можарова Л.Г., Хомицкая Ю.В. Артериальная гипертензия у женщин с климактерическим синдромом. Обзоры клин кардиол 2005;(1):12–9.
5. Шостак Н.А., Аничков Д.А. Эффективность моксонидина у женщин с артериальной гипертензией в рамках метаболического синдрома при исходновысокой частоте сердечных сокращений.
6. Кардиология 2002;42(11):40–3.
7. 2013 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC): ESH/ESC Task Force for the Management of Arterial Hypertension. J Hypertens 2013;31(10):1925–38.
8. Национальные клинические рекомендации: Сборник. Под ред. Р.Г. Оганова. 3-е изд. М.: Силицея-Полиграф, 2010. 592 с.
9. Ванчакова Н.П., Попов А.П. Тревожные расстройства у пациентов с гипертонической болезнью и ишемической болезнью сердца и опыт их коррекции Тенотеном. Поликлиника 2007;(2):74–8.
10. Никольская И.Н., Гусева И.А., Близневская Е.В., Третьякова Т.В. Роль тревожных расстройств при гипертонической болезни и возможности их коррекции. Лечащий врач 2007;(3):89–90.
11. Доскин В.А., Лаврентьев Н.А., Мирошников М.П., Шарай В.Б. Тест дифференцированной самооценки функционального состояния. Вопр психол 1973;(6):141–6.
12. Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol 1959;32(1):50–5.
Review
For citations:
Shostak N.A., Pravdyuk N.G., Anichkov D.A., Kondrashov A.A. HYPERTENSION IN POSTMENOPAUSAL WOMEN: POSSIBILITIES OF COMBINATION THERAPY. The Clinician. 2013;7(3-4):80-86. (In Russ.) https://doi.org/10.17650/1818-8338-2013-3-4-80-86
Views:
1008
Email this article 