SPINAL PAIN SYNDROME: DEVELOPMENT MECHANISMS AND APPROACHES TO COMBINATION THERAPY
https://doi.org/10.17650/1818-8338-2014-8-1-
Abstract
The paper considers an association between spinal pain syndrome and the magnitude of vertebral column changes in osteochondrosis and the specific features and characteristics of pain syndrome. It gives the data that allow the consideration of spinal osteochondrosis as a degenerative and dystrophic process that is concurrent with the compensatory rearrangement of a vertebral motor segment, chiefly a disk, and aimed at adapting the functional capacities of the vertebral column as a whole. The issues of therapy for spinal pain syndrome with a combination of nonsteroidal anti-inflammatory drugs and a vitamin B (B1, B6, and B12) complex are covered.
About the Author
M. Yu. Martynov
N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow
Russian Federation
Russian Federation
References
1. Manchikanti L., Singh V., Datta S. et al. Comprehensive review of epidemiology, scope, and impact of spinal pain. Pain Physician 2009;12(4):E35–70.
2. Pengel L.Н., Herbert R.D., Maher C.G., Refshauge K.M. Acute low back pain: systematic review of its prognosis. BMJ 2003;327(7410):323.
3. Веселовский В.П. Практическая вертеброневрология и мануальная терапия. Рига, 1991.
4. Болевые синдромы в неврологической практике. Под ред. В.Л. Голубева. М.: МЕДпресс-информ, 2010.
5. Иваничев Г.А. Мануальная медицина. Казань, 2000.
6. Jensen M.P., Dworkin R.H., Gammaitoni A.R. et al. Assessment of pain quality in chronic neuropathic and nociceptive pain clinical trials with the Neuropathic Pain Scale. J Pain 2005;6(2):98–106.
7. Попелянский Я.Ю., Штульман Д.Р. Боли в шее, спине и конечностях. В кн.: Болезни нервной системы. Под ред. Н.Н. Яхно, Д.Р. Штульмана. М.: Медицина, 2001. С. 293–316.
8. van Tulder M., Becker A., Bekkering T. et al. Chapter 3. European guidelines for the management of acute nonspecific low back pain in primary care. Eur Spine J 2006; 15 Suppl 2:S169–91.
9. Vining R., Potocki E., Seidman M., Morgenthal A.P. An evidence-based diagnostic classification system for low back pain. J Can Chiropr Assoc 2013;57(3):189–204.
10. Данилов А.Б. Алгоритм диагностики и лечения боли в нижней части спины с точки зрения доказательной медицины. Атмосфера. Нервные болезни 2010;(4): 11–8.
11. Камчатнов П.Р. Применение препаратов Мильгамма и Мильгамма композитум у пациентов с болью в спине. Мед вестн 2010;(4–5):509–10.
12. Khan T.A., Ahmad A., Haider I.Z. Treatment of acute lumbago; low dose diclofenac sodium with vitamin-B complex compared with diclofenac alone. Professional Med J 2008;15(4):440–4.
13. Mauro G.L., Martorana U., Cataldo P. et al. Vitamin B12 in low back pain: a randomised, double-blind, placebocontrolled study. Eur Rev Med Pharmacol Sci 2000;4(3):53–8.
14. Rocha-Gonzalez H.I., Teran-Rosales F., Reyes-Garcia G. et al. B vitamins increase the analgesic effect of diclofenac in the rat. Proc West Pharmacol Soc 2004;47:84–7.
15. Левин О.С., Мосейкин И.А. Комплекс витаминов группы В (Мильгамма) в лечении дискогенной поясничнокрестцовой радикулопатии. Журн неврол психиатр им. С.С. Корсакова 2009; 109(10):30–5.
16. Fu Q.G., Carstens E., Stelzer B., Zimmermann M. B vitamins suppress spinal dorsal horn nociceptive neurons in the cat. Neurosci Lett 1988;95(1–3):192–7.
17. Bromm K., Herrmann W.M., Schulz H. Do the B vitamins exhibit antinociceptive efficacy in men? Results of a placebocontrolled study. Neuropsychobiology 1995;31(3):156–65.
18. Bartoszyk G.D., Wild A. B-vitamins potentiate the antinociceptive effect of diclofenac in carrageenin-induced hyperalgesia in the rat tail pressure test. Neurosci Lett 1989;101(1):95–100.
Review
For citations:
Martynov M.Yu. SPINAL PAIN SYNDROME: DEVELOPMENT MECHANISMS AND APPROACHES TO COMBINATION THERAPY. The Clinician. 2014;8(1):87-90. (In Russ.) https://doi.org/10.17650/1818-8338-2014-8-1-
Views:
923
Email this article 