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OSTEOPOROSIS IN A MALE PATIENT WITH RHEUMATOID ARTHRITIS (A CLINICAL CASE)

https://doi.org/10.17650/1818-8338-2014-1-71-76

Abstract

The paper describes a clinical case of developing rheumatoid arthritis complicated by osteoporosis in a male. It considers the possible risk
factors of osteoporosis and fractures, including those associated with rheumatoid arthritis, the necessity of assessing the 10-year risk of major osteoporotic fractures and femoral neck ones to timely use not only calcium and vitamin D preparations, but also antiosteoporotic therapy to prevent osteoporosis.

About the Authors

A. A. Muradyants
Acad. A.I. Nesterov Department of Faculty Therapy, Faculty of Therapeutics, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow
Russian Federation


N. A. Shostak
Acad. A.I. Nesterov Department of Faculty Therapy, Faculty of Therapeutics, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow
Russian Federation


A. A. Kondrashov
Acad. A.I. Nesterov Department of Faculty Therapy, Faculty of Therapeutics, N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, Moscow
Russian Federation


References

1. Oelzner P., Schwabe A., Lehmann G. et al. Significance of risk factors for osteoporosis is dependent on gender and menopause in rheumatoid arthritis. Rheumatol Int 2008;28(11):1143–50.

2. Kim S. Y., Schneeweiss S., Liu J. et al. Risk of osteoporotic fracture in a large populationbased cohort of patients with rheumatoid arthritis. Arthritis Res Ther 2010;12(4):R154.

3. Haugeberg G., Orstavik R. E., Uhlig T. et al. Bone loss in patients with rheumatoid arthritis: results from a population-based cohort of 366 patients followed up for two years. Arthritis Rheum 2002;46(7):1720–8.

4. Roux C. Osteoporosis in inflammatory joint diseases. Osteoporosis Int 2011;22(2):421–33.

5. Pereira R. M., Carvalho J. F., Canalis E. Glucocorticoid-induced osteoporosis in rheumatic diseases. Clinics (Sao Paulo) 2010;65(11):1197–205.

6. Cawthon P. M. Gender differences in osteoporosis and fractures. Clin Orthop Relat Res 2011;469(7):

7. –5.

8. Jawaheer D., Lum R. F., Gregersen P. K., Criswell L.A. Influence of male sex on disease phenotype in familial rheumatoid arthritis. Arthritis Rheum 2006;54(10):3087–94.

9. Weyand C. M., Schmidt D., Wagner U., Goronzy J. J. The influence of sex on the phenotype of rheumatoid arthritis. Arthritis Rheum 1998;41(5):817–22.

10. Раскина Т. А., Летаева М. В. Минеральная плотность костной ткани у мужчин при различных клинических вариантах ревматоидного артрита. Науч-практ ревматол 2011;(2):21–4.

11. Harman S. M., Metter E. J., Tobin J. D. et al. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab 2001;86(2):724–31.

12. Bhasin S., Cunningham G. R., Hayes F. J. et al. Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2010;95(6):2536–59.

13. Gordon D., Beastall G. H., Thomson J. A. Sturrock R. D. Androgenic status and sexual function in males with rheumatoid arthritis and ankylosing spondylitis. Q J Med 1986;60(231):671–9.

14. Kanis J. A., Johnell O., Odén A. et al. FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int 2008;19(4):385–97.

15. http://www.issam.ch / freetesto.htm.

16. http://www.shef.ac.uk / FRAX / tool. aspx?country=13.

17. Grossman J. M., Gordon R., Ranganath V. K. et al. American College of Rheumatology 2010 recommendations for the prevention and treatment of glucocorticoid induced osteoporosis. Arthritis Care Res (Hoboken) 2010;62(11):1515–26.

18. Vanderschueren D., Vandenput L., Boonen S. et al. Androgens and bone. Endocr Rev 2004;25(3):389–425.

19. Balkan W., Burnstein K. L., Schiller P. C. et al. Androgen-induced mineralization by MC3T3-E1 osteoblastic cells reveals a critical window of hormone responsiveness. Biochem Biophys Res Commun 2005;328(3):783–9.

20. Wiren K. M. Androgens and bone growth: it’s location, location, location. Curr Оpin Рharmacol 2005;5(6):626–32.

21. Edwards C. J., Williams E. The role of interleukin-6 in rheumatoid arthritisassociated osteoporosis. Osteoporos Int 2010;21(8):1287–93.

22. Kalyani R. R., Gavini S., Dobs A. S. Male hypogonadism in systemic disease. Endocrinol Metab Clin North Am 2007;36(2):333–48.

23. Клинические рекомендации. Остеопороз. Диагностика, профилактика и лечение. Под ред. Л. И. Беневоленской, О. М. Лесняк. М.: ГЭОТАР-Медиа, 2009.


Review

For citations:


Muradyants A.A., Shostak N.A., Kondrashov A.A. OSTEOPOROSIS IN A MALE PATIENT WITH RHEUMATOID ARTHRITIS (A CLINICAL CASE). The Clinician. 2014;8(1):71-76. (In Russ.) https://doi.org/10.17650/1818-8338-2014-1-71-76

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ISSN 1818-8338 (Print)
ISSN 2412-8775 (Online)