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ФАКТОРЫ РИСКА СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ У БОЛЬНЫХ С СИНДРОМОМ ОБСТРУКТИВНОГО АПНОЭ СНА

https://doi.org/10.17650/1818-8338-2014-1-15-21

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Аннотация

В статье анализируются причинно-следственные связи синдрома обструктивного апноэ сна (СОАС) и сердечно-сосудистых заболеваний (ССЗ). При СОАС в ответ на интермиттирующую гипоксию и фрагментацию сна происходит активация симпатической нервной системы, провоспалительной и прокоагуляционных систем, эндотелиальная дисфункция и ускоренное развитие атеросклероза, что приводит к увеличению риска ССЗ. Применение CPAP-терапии (Continuous Positive Airway Pressure – постоянное положительное давление в дыхательных путях) снижает риск смерти у больных СОАС.

Об авторах

А. В. Маркин
ГБОУ ВПО «Алтайский государственный медицинский университет» Минздрава России, Барнаул КГБУЗ «Городская больница № 5», Барнаул
Россия


Т. И. Мартыненко
КГБУЗ «Городская больница № 5», Барнаул
Россия


Г. И. Костюченко
КГБУЗ «Краевая клиническая больница», Барнаул
Россия


И. Я. Цеймах
ГБОУ ВПО «Алтайский государственный медицинский университет» Минздрава России, Барнаул
Россия


Я. Н. Шойхет
ГБОУ ВПО «Алтайский государственный медицинский университет» Минздрава России, Барнаул
Россия


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Для цитирования:


Маркин А.В., Мартыненко Т.И., Костюченко Г.И., Цеймах И.Я., Шойхет Я.Н. ФАКТОРЫ РИСКА СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙ У БОЛЬНЫХ С СИНДРОМОМ ОБСТРУКТИВНОГО АПНОЭ СНА. Клиницист. 2014;8(1):15-21. https://doi.org/10.17650/1818-8338-2014-1-15-21

For citation:


Markin A.V., Martynenko T.I., Kostyuchenko G.I., Tseimakh I.Y., Shoikhet Y.N. CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME. The Clinician. 2014;8(1):15-21. (In Russ.) https://doi.org/10.17650/1818-8338-2014-1-15-21

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ISSN 1818-8338 (Print)
ISSN 2412-8775 (Online)