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INFECTIOUS COMPLICATIONS IN PATIENTS WITH LUNG CANCER

https://doi.org/10.17650/1818-8338-2011-1-9-13

Abstract

Lung cancer (LC) annually afflicts 63–65 thousand people in Russia and 1.04 million worldwide, which amounts to 12.8% of all notified cases of neoplasms. In LC patients, infectious complications are characterized by a severe course; destruction foci, decay cavities, and abscess may form.
All give rise to difficulties in making a diagnosis and in choosing a treatment policy. Infections caused by P. aeruginosa, A. baumanii, bacteria of the family Enterobacteriacae, S. aureus, and Enterococcus spp present the greatest problem in inpatients with LC. The early diagnosis of infectious
complications and the use of adequate schemes of antibiotic prevention and therapy promote a reduction in mortality from infection in this category
of patients and expand the possibilities of their specific antitumor treatment.

About the Author

Z. V. Grigoryevskaya
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
Russian Federation
Laboratory of Microbiological Diagnosis and Treatment of Infections in Oncological Care


References

1. Аксель Е.М., Давыдов М.И. Статистика заболеваемости и смертности от злокачественных новообразований в 2000 году. В кн.: Злокачественные новообразования в России и странах СНГ в 2000 г. М.: РОНЦ им. Н.Н. Блохина РАМН, 2002; с. 85–106.

2. Textbook of febrile neutropenia. Rolston K.V.I., Rubenstain E.B. eds. London: Martin Dunitz, 2001.

3. Greene J.N. Infections in cancer patients. NY: Marcel Dekker, 2004.

4. Zeitani J., Penta de Peppo A., De Paulis R., et al. Benefit of partial right-bilateral internal thoracic artery harvesting in patients at risk of sternal wound complications. Ann Thorac Surg 2006;81(1):139–43.

5. Glauser M.P., Pizzo P.A. Management of infections in immunocompromised patients. London: WB Saunders, 2000.

6. Baughman R.P., Morrow E.E. Contemporary diagnosis and management of nosocomial pneumonias. 2nd ed. Pennsylvania: Handbooks in Health Care Co., 2005.

7. Manual of clinical microbiology, 8th ed. Murray P.R., Quayumi S., Johnson J. et al (eds). Washington, D.C.: ASM Press, 2003.

8. Nan D.N., Fernandez-Ayala M., Farinas-Alvarez C., et al. Nosocomial infection after lung surgery: incidence and risk factors. Chest 2005;128:2647–52.

9. Инфекции в онкологии. Под ред. М.И. Давыдова, Н.В. Дмитриевой. М.: Практическая медицина, 2009.

10. Mandell, Douglas, and Bennett's principles and practice of infectious diseases, 7th ed. Philadelphia: Elsevier Churchill Livingstone, 2010.

11. Bergen G.A., Shelhamer J.H. Pulmonary infiltrates in the cancer patient. New approaches

12. to an old problem. Infect Dis Clin North Am 1996;10:297–325.

13. Lister P.D., Wolter D.J., Hanson N.D. Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clin Microbiol Rev 2009;22(4):582–610.

14. Wiener J., Quinn J.P., Bradford P.A., et al. Multiple antibiotic-resistant Klebsiella and Escherichia coli in nursing homes. JAMA 1999;281:517–23.

15. Wunderink R.G., Rello J., Cammarata S.K., et al. Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillinresistant Staphylococcus aureus nosocomial pneumonia. Chest 2003;124(5):1789–97 .

16. Антимикробные препараты и стандарты лечения инфекционных осложнений у онкологических больных. Под ред. Н.В. Дмитриевой. М.: Практическая медицина, 2011.


Review

For citations:


Grigoryevskaya Z.V. INFECTIOUS COMPLICATIONS IN PATIENTS WITH LUNG CANCER. The Clinician. 2011;5(1):9-13. (In Russ.) https://doi.org/10.17650/1818-8338-2011-1-9-13

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ISSN 1818-8338 (Print)
ISSN 2412-8775 (Online)