Quarterly color scientific and practical peer-reviewed journal, included into the publications listing of State Commission for Academic Degrees and Titles. Founded in 2005. 
The journal is included into the list of leading peer-reviewed journals in which major scientific results of theses for degrees of PhD and Doctor of Science are published.

The journal contains scientific reviews, lectures of leading national and international specialists, original research devoted to internal diseases including cardiologic, pulmonary, neurologic, endocrinologic, rheumatologic diseases, etc. The journal contains clinical works, translated articles, presentations of state-of-art technologies of diagnostics, therapy, and prevention of internal diseases, and, among everything else, the section of "Aid to a polyclinic doctor", "For a future clinician", "Wordings of main diagnoses for internal diseases". 

Members of the editorial board and authors of the journal are leading Russian and foreign general practitioners, cardiologists, pediatricians, immunologists.

The Editor-in-Chief is Nadezhda A. Shostak, Professor, Honored Doctor of the Russian Federation, Head Academician A.I. Nesterov Department of Intermediate Level Therapy of the Russian State Medical University. 

Periodicity of issue is 4 issues per year, the volume is 72 to 100 pages.