Clinical case of an acquired hemophilia
https://doi.org/10.17650/1818-8338-2019-13-3-4-74-77
Abstract
The aim of the work is to describe the clinical case of formation, diagnosis and treatment of the acquired form of blood clotting factor VIII deficiency – of acquired hemophilia A.
Material and methods. Patient R., 71 years, from April 2018, was found an acute hemorrhagic syndrome in the hematomic type of large hematomas manifested submandibular region, neck, chest, right breast, pubic and inguinal regions on the right, the anterior-medial surface of the left femur, anterior surface of left tibia. Standard laboratory tests, computed tomography of soft tissues of the neck, lungs, abdomen; coagulogram; blood clotting factors; inhibitor of factor VIII were evaluated in dynamics during the patient’s stay in the hospital; platelet aggregation function.
Results. Typical gematomny type of bleeding, prolongation of coagulation indicators, the presence of the inhibitor factor VIII (7,0 BAA), the decrease in factor VIII (2 %) allowed diagnosis of acquired hemophilia A. Anti-inhibitory coagulant complex, fresh frozen plasma was successfully used for treatment. The patient is under observation in the regional Hematology center. The hematomas were not renewed.
Conclusion. Our clinical observation demonstrates the features of the course, the algorithm of diagnosis and management of patients with of acquired hemophilia A.
About the Authors
P. N. Barlamov
Perm State Medical University named after E.A. Wagner of the Ministry of Healthcare of the Russian Federation
Russian Federation
26 Petropavlovskaya St., Perm 614990
Russian Federation
26 Petropavlovskaya St., Perm 614990
E. R. Vasilyeva
Medical Unit № 1
Russian Federation
68 Gagarina Bul’var, Perm 614077
Russian Federation
68 Gagarina Bul’var, Perm 614077
M. E. Golubeva
Medical Unit № 1
Russian Federation
68 Gagarina Bul’var, Perm 614077
Russian Federation
68 Gagarina Bul’var, Perm 614077
V. G. Zhelobov
Perm State Medical University named after E.A. Wagner of the Ministry of Healthcare of the Russian Federation
Russian Federation
26 Petropavlovskaya St., Perm 614990
Russian Federation
26 Petropavlovskaya St., Perm 614990
A. A. Shutylev
Perm Regional Clinical Hospital
Russian Federation
85 Pushkina St., Perm 614990
Russian Federation
85 Pushkina St., Perm 614990
T. Yu. Kravtsova
Perm State Medical University named after E.A. Wagner of the Ministry of Healthcare of the Russian Federation
Russian Federation
26 Petropavlovskaya St., Perm 614990
Russian Federation
26 Petropavlovskaya St., Perm 614990
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Review
For citations:
Barlamov P.N., Vasilyeva E.R., Golubeva M.E., Zhelobov V.G., Shutylev A.A., Kravtsova T.Yu. Clinical case of an acquired hemophilia. The Clinician. 2019;13(3-4):74-77. (In Russ.) https://doi.org/10.17650/1818-8338-2019-13-3-4-74-77
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