The ClinicianThe ClinicianКлиницист1818-83382412-8775Publishing House ABV Press710.17650/1818-8338-2013-3-4-27-3REVIEWОБЗОРARTERIAL STIFFNESS IN CHRONIC HEART FAILUREЖЕСТКОСТЬ СОСУДИСТОЙ СТЕНКИ ПРИ ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИDrapkinaO. M.ДрапкинаО. М.
Russian Federation
DadaevaV. A.ДадаеваВ. А.
Russian Federation
dr.dadaeva@mail.ruI.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России1510201373-42731407201414072014Copyright ©; 2013, Drapkina O.M., Dadaeva V.A.Copyright ©; 2013, Драпкина О.М., Дадаева В.А.2013Drapkina O.M., Dadaeva V.A.Драпкина О.М., Дадаева В.А.https://creativecommons.org/licenses/by/4.0https://klinitsist.abvpress.ru/Klin/article/view/7

Nearly half of patients with chronic heart failure (CHF) have a preserved left ventricular ejection fraction, known as diastolic heart failure. Echocardiography is the primary modality for evaluating left ventricular (LV) systolic and diastolic function in CHF patients. LV developedpressure (dP/dt) is a classical index of myocardial contractility. At the same time, pulse wave velocity, which has been used as a measure of arterial stiffness, can be used as an index of LV contractile function. The maximal dP/dt of the radial pulse appears to be a good and reproducible criterion of LV systolic performance with high potential as a diagnostic method.

Почти у половины пациентов с хронической сердечной недостаточностью (ХСН) обнаруживается сохраненная фракция выброса (СФВ) левого желудочка (ЛЖ), состояние, известное как диастолическая ХСН. Эхокардиография в настоящее время является основным диагностическим методом для оценки систолической и диастолической функции ЛЖ у пациентов с ХСН. Классический показатель сократительной функции ЛЖ – максимально достигнутое систолическое давление (dP/dt) в ЛЖ. В то же время скорость пульсовой волны, применяемая для оценки ригидности артериальной стенки, может использоваться и в качестве показателя сократительной функции ЛЖ. На лучевой артерии dP/dt – важный и воспроизводимый показатель сократительной функции ЛЖ с высоким диагностическим потенциалом.

arterial stiffnessdiastolic heart failurepreserved left ventricular ejection fractionpulse wave velocityжесткость артериальной стенкидиастолическая сердечная недостаточностьсохраненная фракция выброса левого желудочкаскорость пульсовой волны1. Смирнова Е. А. Изучение распространенности и этиологии хронической сердечной недостаточности в Рязанской области. Рос кардиол журн 2010;(2):78–83.Смирнова Е. А. Изучение распространенности и этиологии хронической сердечной недостаточности в Рязанской области. Рос кардиол журн 2010;(2):78–83.2. McCullough P.A., Philbin E. F., Spertus J. A. et al. Confirmation of a heart failure epidemic: findings from the Resource Utilization Among Congestive Heart Failure (REACH) study. J Am Coll Cardiol 2002;39(1):60–9.McCullough P.A., Philbin E. F., Spertus J. A. et al. Confirmation of a heart failure epidemic: findings from the Resource Utilization Among Congestive Heart Failure (REACH) study. J Am Coll Cardiol 2002;39(1):60–9.3. Hunt S. A., Abraham W. T., Chin M. H. et al. 2009 focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation. Circulation 2009;119(14):е391–479.Hunt S. A., Abraham W. T., Chin M. H. et al. 2009 focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with the International Society for Heart and Lung Transplantation. Circulation 2009;119(14):е391–479.4. Owan T. E., Hodge D. O., Herges R. M. et al. Trends in prevalence and outcome of heart failure with preserved ejection fraction. N Engl J Med 2006;355(3):251–9.Owan T. E., Hodge D. O., Herges R. M. et al. Trends in prevalence and outcome of heart failure with preserved ejection fraction. N Engl J Med 2006;355(3):251–9.5. Westermann D., Kasner M., Steendijk P. et al. Role of left ventricular stiffness in heart failure with normal ejection fraction. Circulation 2008;117(16):2051–60.Westermann D., Kasner M., Steendijk P. et al. Role of left ventricular stiffness in heart failure with normal ejection fraction. Circulation 2008;117(16):2051–60.6. Badano L. P., Albanese M. C., De Biaggio P. et al. Prevalence, clinical characteristics, quality of life, and prognosis of patients with congestive heart failure and isolated left ventricular diastolic dysfunction. J Am Soc Echocardiogr 2004;17(3):253–61.Badano L. P., Albanese M. C., De Biaggio P. et al. Prevalence, clinical characteristics, quality of life, and prognosis of patients with congestive heart failure and isolated left ventricular diastolic dysfunction. J Am Soc Echocardiogr 2004;17(3):253–61.7. Bhatia R. S., Tu J. V., Lee D. S. et al. Outcome of heart failure with preserved ejection fraction in a population-based study. N Engl J Med 2006;355(3):260–9.Bhatia R. S., Tu J. V., Lee D. S. et al. Outcome of heart failure with preserved ejection fraction in a population-based study. N Engl J Med 2006;355(3):260–9.8. Paulus W. J., Tschope C., Sanderson J. E. et al. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. Eur Heart J 2007;28(20):2539–50.Paulus W. J., Tschope C., Sanderson J. E. et al. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. Eur Heart J 2007;28(20):2539–50.9. Gandhi S. K., Powers J. C., Nomeir A. M. et al. The pathogenesis of acute pulmonary edema associated with hypertension. N Engl J Med 2001;344(1):17–22.Gandhi S. K., Powers J. C., Nomeir A. M. et al. The pathogenesis of acute pulmonary edema associated with hypertension. N Engl J Med 2001;344(1):17–22.10. Kawaguchi M., Hay I., Fetics B., Kass D. A. Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: Implications for systolic and diastolic reserve limitations. Circulation 2003;107(5):714–20.Kawaguchi M., Hay I., Fetics B., Kass D. A. Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: Implications for systolic and diastolic reserve limitations. Circulation 2003;107(5):714–20.11. Westerhof N., O'Rourke M. F. Haemodynamic basis for the development of left ventricular failure in systolic hypertension and for its logical therapy. J Hypertens 1995;13(9):943–52.Westerhof N., O'Rourke M. F. Haemodynamic basis for the development of left ventricular failure in systolic hypertension and for its logical therapy. J Hypertens 1995;13(9):943–52.12. Овчинников А. Г., Агеев Ф. Т., Свирида О. Н. Патогенетический подход к терапии пациентов с хронической сердечной недостаточностью и сохраненной систолической функцией левого желудочка. Кардиол вестн 2011;(1):33–9.Овчинников А. Г., Агеев Ф. Т., Свирида О. Н. Патогенетический подход к терапии пациентов с хронической сердечной недостаточностью и сохраненной систолической функцией левого желудочка. Кардиол вестн 2011;(1):33–9.13. Wang M., Yip G. W., Wang A. Y. et al. Tissue Doppler imaging provides incremental prognostic value in patients with systemic hypertension and left ventricular hypertrophy. J Hypertens 2005;23(1):183–91.Wang M., Yip G. W., Wang A. Y. et al. Tissue Doppler imaging provides incremental prognostic value in patients with systemic hypertension and left ventricular hypertrophy. J Hypertens 2005;23(1):183–91.14. Majeed A., Williams.J, de Lusignan S., Chan T. Management of heart failure in primary care after implementation of the National Service Framework for Coronary Heart Disease: a cross-sectional study. Public Health 2005;119(2):105–11.Majeed A., Williams.J, de Lusignan S., Chan T. Management of heart failure in primary care after implementation of the National Service Framework for Coronary Heart Disease: a cross-sectional study. Public Health 2005;119(2):105–11.15. Зборовская И. А., Чернова С. И. Изменение скорости пульсовой волны и содержание антител к коллагену I и III типа как показатели сосудистого ремоделирования у больных с сердечной недостаточностью. Справочник врача общей практики 2010;(9):37–40.Зборовская И. А., Чернова С. И. Изменение скорости пульсовой волны и содержание антител к коллагену I и III типа как показатели сосудистого ремоделирования у больных с сердечной недостаточностью. Справочник врача общей практики 2010;(9):37–40.16. Harada Y., Sugarawa M., Beppu T. et al. Principle of non-invasive method of measuring Max (dP/dt) of the left ventricle: theory and experiments. Heart Vessels 1987;3(1):25–32.Harada Y., Sugarawa M., Beppu T. et al. Principle of non-invasive method of measuring Max (dP/dt) of the left ventricle: theory and experiments. Heart Vessels 1987;3(1):25–32.17. Ohte N., Narita H., Sugarawa M. et al. Clinical usefulness of carotid arterial wave intensity in assessing left ventricular systolic and early diastolic performance. Heart Vessels 2003;18(3):107–11.Ohte N., Narita H., Sugarawa M. et al. Clinical usefulness of carotid arterial wave intensity in assessing left ventricular systolic and early diastolic performance. Heart Vessels 2003;18(3):107–11.18. Chiu Y. C., Arand P. W., Shroff S. G. et al. Determination of pulse wave velocities with computerized algorithms. Am Heart J 1991;121(5):1460–70.Chiu Y. C., Arand P. W., Shroff S. G. et al. Determination of pulse wave velocities with computerized algorithms. Am Heart J 1991;121(5):1460–70.19. Tartiere J. M., Logeart D., Beauvais F. et al. Non-invasive radial pulse wave assessment for the evaluation of left ventricular systolic performance in heart failure. Eur J Heart Fail 2007;9(5):477–83.Tartiere J. M., Logeart D., Beauvais F. et al. Non-invasive radial pulse wave assessment for the evaluation of left ventricular systolic performance in heart failure. Eur J Heart Fail 2007;9(5):477–83.20. Осмоловская Ю. Ф., Глечан А. М., Мареев В. Ю. Жесткость артериальной стенки у пациентов с хронической сердечной недостаточностью со сниженной и сохранной систолической функцией левого желудочка. Кардиология 2010;50(10):86–92.Осмоловская Ю. Ф., Глечан А. М., Мареев В. Ю. Жесткость артериальной стенки у пациентов с хронической сердечной недостаточностью со сниженной и сохранной систолической функцией левого желудочка. Кардиология 2010;50(10):86–92.21. Stewart A. D., Millasseau S. C., Kearney M. T. et al. Effects of inhibition of basal nitric oxide synthesis on carotid-femoral pulse wave velocity and augmentation index in humans. Hypertension 2003;42(5):915–8.Stewart A. D., Millasseau S. C., Kearney M. T. et al. Effects of inhibition of basal nitric oxide synthesis on carotid-femoral pulse wave velocity and augmentation index in humans. Hypertension 2003;42(5):915–8.22. Yambe M., Tomiyama H., Hirayama Y. et al. Arterial stiffening as a possible risk factor for both atherosclerosis and diastolic heart failure. Hypertens Res 2004;27(9):625–31.Yambe M., Tomiyama H., Hirayama Y. et al. Arterial stiffening as a possible risk factor for both atherosclerosis and diastolic heart failure. Hypertens Res 2004;27(9):625–31.23. Meguro T., Nagatomo Y., Nagae A. et al. Elevated arterial stiffness evaluated by brachial-ankle pulse wave velocity is deleterious for the prognosis of patients with heart failure. Circ J 2009;73(4):673–80.Meguro T., Nagatomo Y., Nagae A. et al. Elevated arterial stiffness evaluated by brachial-ankle pulse wave velocity is deleterious for the prognosis of patients with heart failure. Circ J 2009;73(4):673–80.24. Shiba N., Watanabe J., Shinozaki T. et al. Analysis of chronic heart failure registry in the Tohoku district: third year follow-up. Circ J 2004;68(5):427–34.Shiba N., Watanabe J., Shinozaki T. et al. Analysis of chronic heart failure registry in the Tohoku district: third year follow-up. Circ J 2004;68(5):427–34.25. Benetos A., Safar M., Rudnichi A. et al. Pulse pressure: a predictor of long-term cardiovascular mortality in a French male population. Hypertension 1997;30(6):1410–5.Benetos A., Safar M., Rudnichi A. et al. Pulse pressure: a predictor of long-term cardiovascular mortality in a French male population. Hypertension 1997;30(6):1410–5.26. Mattace-Raso F. U., van der Cammen T. J., Hofman A. et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam study. Circulation 2006;113(5):657–63.Mattace-Raso F. U., van der Cammen T. J., Hofman A. et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam study. Circulation 2006;113(5):657–63.27. Weber T., Auer J., O’Rourke M. F. et al. Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions. Eur Heart J 2005;26(24):2657–63.Weber T., Auer J., O’Rourke M. F. et al. Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions. Eur Heart J 2005;26(24):2657–63.28. Vaccarino V., Holford T. R., Krumholz H. M. Pulse pressure and risk for myocardial infarction and heart failure in the elderly. J Am Coll Cardiol 2000;36(1):130–8.Vaccarino V., Holford T. R., Krumholz H. M. Pulse pressure and risk for myocardial infarction and heart failure in the elderly. J Am Coll Cardiol 2000;36(1):130–8.29. Mitchell G. F., Moye L. A., Braunwald E. et al. Sphygmomanometrically determined pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular function. SAVE investigators. Survival and Ventricular Enlargement. Circulation 1997;96(12):4254–60.Mitchell G. F., Moye L. A., Braunwald E. et al. Sphygmomanometrically determined pulse pressure is a powerful independent predictor of recurrent events after myocardial infarction in patients with impaired left ventricular function. SAVE investigators. Survival and Ventricular Enlargement. Circulation 1997;96(12):4254–60.30. Domanski M. J., Mitchell G. F., Norman J. E. et al. Independent prognostic information provided by sphygmomanometrically determined pulse pressure and mean arterial pressure in patients with leftDomanski M. J., Mitchell G. F., Norman J. E. et al. Independent prognostic information provided by sphygmomanometrically determined pulse pressure and mean arterial pressure in patients with leftventricular dysfunction. J Am Coll Cardiol 1999;33(4):951–8.31. Voors A. A., Petrie C. J., Petrie M. C. et al. Low pulse pressure is independently related to elevated natriuretic peptides and increased mortality in advanced chronic heart failure. Eur Heart J 2005;26(17):1759–64.Voors A. A., Petrie C. J., Petrie M. C. et al. Low pulse pressure is independently related to elevated natriuretic peptides and increased mortality in advanced chronic heart failure. Eur Heart J 2005;26(17):1759–64.32. Weber T., Auer J., Lamm G. et al. Arterial stiffness, central blood pressures, and wave reflections in cardiomyopathy-implications for risk stratification. J Card Fail 2007;13(5):353–9.Weber T., Auer J., Lamm G. et al. Arterial stiffness, central blood pressures, and wave reflections in cardiomyopathy-implications for risk stratification. J Card Fail 2007;13(5):353–9.33. Mitchell G. F., Tardiff J. C., Arnold J. M. et al. Pulsatile hemodynamics in congestive heart failure. Hypertension 2001;38(6):1433–9.Mitchell G. F., Tardiff J. C., Arnold J. M. et al. Pulsatile hemodynamics in congestive heart failure. Hypertension 2001;38(6):1433–9.34. O’Rourke M. F., Hayward C. S. Arterial stiffness, gender and heart rate. J Hypertens 2003;21(3):487–90.O’Rourke M. F., Hayward C. S. Arterial stiffness, gender and heart rate. J Hypertens 2003;21(3):487–90.35. Nurnberger J., Opazo Saez A., Dammer S. et al. Left ventricular ejection time: a potential determinant of pulse wave velocity in young, healthy males. J Hypertens 2003;21(11):2125–32.Nurnberger J., Opazo Saez A., Dammer S. et al. Left ventricular ejection time: a potential determinant of pulse wave velocity in young, healthy males. J Hypertens 2003;21(11):2125–32.36. Tartière J. M., Logeart D., Safar M. E., Cohen-Solal A. Interaction between pulse wave velocity, augmentation index, pulse pressure and left ventricular function in chronic heart failure. J Hum Hypertens 2006;20(3):213–9.Tartière J. M., Logeart D., Safar M. E., Cohen-Solal A. Interaction between pulse wave velocity, augmentation index, pulse pressure and left ventricular function in chronic heart failure. J Hum Hypertens 2006;20(3):213–9.37. Kawaguchi M., Hay I., Fetics B., Kass D. A. Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction. Implications for systolic and diastolic reserve limitations. Circulation 2003;107(5):714–20.Kawaguchi M., Hay I., Fetics B., Kass D. A. Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction. Implications for systolic and diastolic reserve limitations. Circulation 2003;107(5):714–20.38. Pepine C. J., Nichols W. W., Conti R. Aortic input impedance in heart failure. Circulation 1978;58(3 Pt 1):460–5.Pepine C. J., Nichols W. W., Conti R. Aortic input impedance in heart failure. Circulation 1978;58(3 Pt 1):460–5.39. Kromer E. P., Elsner D., Holmer S. R. et al. Aortic input impedance and neurohormonal activation in patients with mild to moderate chronic congestive heart failure. Cardiovasc Res 1992;26(3):265–72.Kromer E. P., Elsner D., Holmer S. R. et al. Aortic input impedance and neurohormonal activation in patients with mild to moderate chronic congestive heart failure. Cardiovasc Res 1992;26(3):265–72.40. Giannattasio C., Failla M., Stella M. L. et al. Alterations of radial artery compliance in patients with congestive heart failure. Am J Cardiol 1995;76(5):381–5.Giannattasio C., Failla M., Stella M. L. et al. Alterations of radial artery compliance in patients with congestive heart failure. Am J Cardiol 1995;76(5):381–5.41. Khder Y., el Ghawi R., Bray des Boscs L. B. et al. Investigations of the peripheral vascular mechanisms implicated in congestive heart failure by the non invasive evaluation of radial artery compliance and reactivity. Int J Cardiol 1996;56(2):149–58.Khder Y., el Ghawi R., Bray des Boscs L. B. et al. Investigations of the peripheral vascular mechanisms implicated in congestive heart failure by the non invasive evaluation of radial artery compliance and reactivity. Int J Cardiol 1996;56(2):149–58.