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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">692</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2025-19-4-K767</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>PHARMACOTHERAPY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ФАРМАКОТЕРАПИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Post-stroke rehabilitation with a focus on motor and cognitive recovery</article-title><trans-title-group xml:lang="ru"><trans-title>Реабилитация после инсульта с акцентом на двигательное и когнитивное восстановление</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7264-3580</contrib-id><name-alternatives><name xml:lang="en"><surname>Barulin</surname><given-names>Aleksandr E.</given-names></name><name xml:lang="ru"><surname>Барулин</surname><given-names>Александр Евгеньевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>barulin23@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4364-0123</contrib-id><name-alternatives><name xml:lang="en"><surname>Kurushina</surname><given-names>O. V.</given-names></name><name xml:lang="ru"><surname>Курушина</surname><given-names>О. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>barulin23@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6517-9062</contrib-id><name-alternatives><name xml:lang="en"><surname>Chernovolenko</surname><given-names>E. P.</given-names></name><name xml:lang="ru"><surname>Черноволенко</surname><given-names>Е. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>barulin23@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Volgograd State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Волгоградский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2026-03-17" publication-format="electronic"><day>17</day><month>03</month><year>2026</year></pub-date><volume>19</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>87</fpage><lpage>95</lpage><history><date date-type="received" iso-8601-date="2026-03-16"><day>16</day><month>03</month><year>2026</year></date><date date-type="accepted" iso-8601-date="2026-03-16"><day>16</day><month>03</month><year>2026</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2026, Barulin A.E., Kurushina O.V., Chernovolenko E.P.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2026, Барулин А.Е., Курушина О.В., Черноволенко Е.П.</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="en">Barulin A.E., Kurushina O.V., Chernovolenko E.P.</copyright-holder><copyright-holder xml:lang="ru">Барулин А.Е., Курушина О.В., Черноволенко Е.П.</copyright-holder><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/692">https://klinitsist.abvpress.ru/Klin/article/view/692</self-uri><abstract xml:lang="en"><p>The relevance of neurorehabilitation research is determined by the high incidence of acute cerebrovascular pathologies, as well as the increasing risk of disability due to residual impairment after a stroke. Severe motor impairment in the limbs, static and gait disorders, and decreased intellectual and memory functions significantly reduce the quality of life of patients and increase the demand for rehabilitation services. The work considers the fundamental principles of neurorehabilitation: early initiation, comprehensiveness, consistency, interdisciplinary approach, and the appropriate combination of drug and non-drug therapies. The main approaches to motor rehabilitation for patients after a stroke are described in detail, and key areas for stroke recurrence prevention are highlighted. Physical rehabilitation methods include kinesitherapy, occupational therapy, gait training, mechanotherapy, neurodevelopment techniques, and motor control restoration using robotic devices based on biofeedback. Various physiotherapeutic approaches (massage, manual therapy, acupuncture, cryotherapy, magnetic and electrical stimulation technologies) are used as adjunctive methods to enhance the effectiveness of motor rehabilitation. Medicines and rehabilitation methods are presented through the prism of evidence-based medicine. Particular importance is given to the correction of cognitive disorders, since their preservation directly affects the success of recovery. Cognitive rehabilitation includes the use of external compensatory strategies, metacognitive training, environmental adaptation with scanning training and multisensory stimulation methods, speech exercises, as well as various computer programs and paper-based methods with training in concentration, rapid selection and switching of attention. The mechanism of action and proven efficacy of choline alfoscerate (Cereton), a multifunctional drug, are demonstrated; its use as part of a comprehensive rehabilitation program significantly improves patients’ cognitive state and enhances their adaptive capacity.</p></abstract><trans-abstract xml:lang="ru"><p>Актуальность темы нейрореабилитации определяется высокой частотой случаев острых цереброваскулярных патологий, а также увеличивающимся риском формирования инвалидности вследствие остаточных нарушений после инсульта. Выраженный моторный дефект в конечностях, нарушение статики, ходьбы, снижение интеллектуально-мнестических функций в большей степени снижают качество жизни пациентов и увеличивают спрос на реабилитационные услуги. В работе отражены базовые принципы нейрореабилитации – раннее начало, комплексность, последовательность, междисциплинарный подход, а также целесообразное сочетание медикаментозной и немедикаментозной терапии. Подробно описаны основные подходы к двигательной реабилитации пациентов после перенесенного инсульта, отмечены ключевые направления профилактики рецидивов инсульта. Среди методик физической реабилитации выделяют кинезиотерапию, эрготерапию, обучение ходьбе, механотерапию, методики нейроразвития и восстановления контроля движений с помощью роботизированных устройств, основанных на биологической обратной связи. В качестве вспомогательных методов, усиливающих эффект двигательной реабилитации, применяют различные подходы физиотерапевтического воздействия (массаж, мануальная терапия, акупунктура, криотерапия, технологии магнитной и электростимуляции). Лекарственные средства и реабилитационные методики представлены через призму доказательной медицины. Особое значение отведено коррекции когнитивных расстройств, поскольку их сохранность напрямую влияет на успех восстановления. Когнитивная реабилитация включает использование внешних компенсаторных стратегий, метакогнитивный тренинг, адаптацию среды с тренировкой сканирования и методов мультисенсорной стимуляции, речевые упражнения, а также компьютерные программы и «бумажные» методики с тренировкой концентрации, быстрого выбора и переключения внимания. Продемонстрированы механизм действия и подтвержденная эффективность холина альфосцерата (Церетона), обладающего многофункциональным воздействием. Его применение в составе комплексной реабилитации заметно улучшает когнитивное состояние пациентов и усиливает их адаптационные возможности.</p></trans-abstract><kwd-group xml:lang="en"><kwd>stroke</kwd><kwd>motor rehabilitation</kwd><kwd>neurorehabilitation</kwd><kwd>neuroplasticity</kwd><kwd>cognitive rehabilitation</kwd><kwd>biofeedback</kwd><kwd>physical therapy method</kwd><kwd>evidence-based medicine</kwd><kwd>choline alfoscerate</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>инсульт</kwd><kwd>двигательная реабилитация</kwd><kwd>нейрореабилитация</kwd><kwd>нейропластичность</kwd><kwd>когнитивная реабилитация</kwd><kwd>биологическая обратная связь</kwd><kwd>метод физиотерапии</kwd><kwd>доказательная медицина</kwd><kwd>холина альфосцерат</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Feigin V.L., Stark B.A., Johnson C.O. et al. 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