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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">626</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2024-18-4-K729</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>LECTION</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ЛЕКЦИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Modern possibilities of echocardiographic diagnosis in pulmonary arterial hypertension</article-title><trans-title-group xml:lang="ru"><trans-title>Современные возможности эхокардиографической диагностики при легочной артериальной гипертензии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7410-9784</contrib-id><name-alternatives><name xml:lang="en"><surname>Klimenko</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Клименко</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Alesya Aleksandrovna Klimenko</p><p>117997; 1 Ostrovitianov St.; 119049; 8 Leninskiy Avenue; Moscow</p></bio><bio xml:lang="ru"><p>Алеся Александровна Клименко</p><p>117513; ул. Островитянова, 1; 119049; Ленинский проспект, 8; Москва</p></bio><email>aaklimenko@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7034-8382</contrib-id><name-alternatives><name xml:lang="en"><surname>Bogdanova</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Богданова</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>119048; 8 / 2 Trubetskaya St.; Moscow</p></bio><bio xml:lang="ru"><p>119048; ул. Трубецкая, 8 / 2; Москва</p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8302-6916</contrib-id><name-alternatives><name xml:lang="en"><surname>Mareeva</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Мареева</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>117997; 1 Ostrovitianov St.; Moscow</p></bio><bio xml:lang="ru"><p>117513; ул. Островитянова, 1; Москва</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н. И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.I. Pirogov City Clinical Hospital No. 1, Moscow Healthcare Department</institution></aff><aff><institution xml:lang="ru">ГБУЗ г. Москвы «Городская клиническая больница № 1 им. Н. И. Пирогова Департамента здравоохранения г. Москвы»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2024</year></pub-date><volume>18</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>44</fpage><lpage>58</lpage><history><date date-type="received" iso-8601-date="2025-01-27"><day>27</day><month>01</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-01-27"><day>27</day><month>01</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Klimenko A.A., Bogdanova A.A., Mareeva V.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Клименко А.А., Богданова А.А., Мареева В.А.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Klimenko A.A., Bogdanova A.A., Mareeva V.A.</copyright-holder><copyright-holder xml:lang="ru">Клименко А.А., Богданова А.А., Мареева В.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/626">https://klinitsist.abvpress.ru/Klin/article/view/626</self-uri><abstract xml:lang="en"><p>   Pulmonary Hypertension (PH) is a hemodynamic and pathophysiological condition characterized by an increase in mean pulmonary artery (PA) pressure by at least 20 mm Hg at rest, measured during right heart catheterization. One of the fastest and most accessible screening non-invasive diagnostic methods for assessing the likelihood of this condition is echocardiography, which is performed according to the standard transthoracic echocardiography protocol, focusing on visualizing and describing certain parameters that characterize function of heart right chambers. In patients with PH, structural changes in the heart right chambers can be observed, such as enlargement of the right atrium and right ventricle, changes in their geometric shape, thickening right ventricle wall, dilatation of the main PA and its branches, and the appearance of tricuspid regurgitation. Pulmonary artery pressure can be measured using either the velocity of the tricuspid regurgitant jet or the ratio of the time acceleration of flow in the outflow tract of the right ventricle to the ejection time (mean pressure in the PA), or the velocity of the pulmonary regurgitation jet (end-diastolic pressure in the PA). Classic parameters of the functional state of the right ventricle, as well as additional indicators of the evaluation of the right ventricular function, for example, the ratio of the amplitude of movement of the fibrous ring to systolic pressure in the PA, called the right ventriculoarterial coupling, should be evaluated only in expert centers providing care for patients with PH. Correct and timely diagnosis, clear dynamic monitoring of the patient’s condition play a crucial role in prescribing targeted treatment and predicting the disease course.</p></abstract><trans-abstract xml:lang="ru"><p>   Легочная гипертензия (ЛГ) – это гемодинамическое и патофизиологическое состояние, которое характеризуется повышением среднего давления в легочной артерии (ЛА) не менее чем на 20 мм рт. ст. в покое, выявленным при чрезвенозной катетеризации сердца. Чтобы оценить вероятность наличия ЛГ, применяют один из быстрых и доступных скрининговых неинвазивных методов диагностики – эхокардиографическое (ЭхоКГ) исследование. Его проводят по стандартному трансторакальному ЭхоКГ-протоколу, при этом прицельно визуализируют и описывают ряд параметров функции правых камер сердца. У пациентов с ЛГ можно наблюдать такие структурные изменения правых камер сердца, как увеличение размеров правого предсердия и правого желудочка (ПЖ), изменение их геометрической формы, утолщение стенки ПЖ, дилатация ствола ЛА и ее ветвей, а также появление трикуспидальной регургитации. Расчет давления в ЛА можно провести как по скорости струи трикуспидальной регургитации, так и по отношению времени ускорения потока в выносящем тракте ПЖ к времени выброса (среднее давление в ЛА), а также по скорости потока легочной регургитации (конечно-диастолическое давление в ЛА). Классические параметры функционального состояния ПЖ, а также дополнительные показатели оценки функции ПЖ (например, соотношение амплитуды движения фиброзного кольца к систолическому давлению в ЛА, которое назвали правожелудочково-артериальным сопряжением) необходимо оценивать только в экспертных центрах по оказанию помощи пациентам с ЛГ. Правильная и своевременная постановка диагноза, четкий динамический контроль состояния пациента имеют решающее значение в назначении таргетного лечения и прогнозе заболевания.</p></trans-abstract><kwd-group xml:lang="en"><kwd>pulmonary hypertension</kwd><kwd>echocardiography</kwd><kwd>pulmonary artery</kwd><kwd>right ventricle</kwd><kwd>heart failure</kwd><kwd>prognosis</kwd><kwd>riociguat</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>легочная гипертензия</kwd><kwd>эхокардиография</kwd><kwd>легочная артерия</kwd><kwd>правый желудочек</kwd><kwd>сердечная недостаточность</kwd><kwd>прогноз</kwd><kwd>риоцигуат</kwd></kwd-group><funding-group><funding-statement xml:lang="en">The work was performed without external funding</funding-statement><funding-statement xml:lang="ru">Работа выполнена без спонсорской поддержки</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Chazova I.E., Martynyuk T.V., Shmalts A.A. et al. 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