The ClinicianThe ClinicianКлиницист1818-83382412-8775Publishing House ABV Press6110.17650/1818-8338-2012-3-4-80-84PHARMACOTHERAPYФАРМАКОТЕРАПИЯUse of statins in cardiorenal syndrome : possibilities for its treatment and preventionПрименение статинов при кардиоренальном синдроме: возможности лечения и профилактикиMinasyanA. M.МинасянА. М.
Russian Federation

Therapy Department Three

Кафедра терапии № 3

armine_minasyan@yahoo.comM. Geratsi Yerevan State Medical UniversityЕрГМУ им. М. Гераци1510201263-480841507201415072014Copyright ©; 2012, Minasyan A.M.Copyright ©; 2012, Минасян А.М.2012Minasyan A.M.Минасян А.М.https://creativecommons.org/licenses/by/4.0https://klinitsist.abvpress.ru/Klin/article/view/61

Cardiovascular diseases are the major cause of disease and death not only in the general population, but also in patients with chronic kidney disease. The growing morbidity and mortality from chronic kidney disease and chronic heart failure conduce to an increase in cases of cardiorenal syndrome. Along with angiotensin-converting enzyme inhibitors, β-adrenoblockers, antianemic drugs, and diuretics, statins are appropriate and recommended by a number of trials for the prevention and treatment of the cardiorenal syndrome. Statins are effective in preventing the cardiorenal syndrome in patients at its high risk, improve quality of life and survival; in predialysis patients with chronic kidney disease, they may be secondary prevention of cardiovascular death.

Сердечно-сосудистые заболевания – главная причина заболеваемости и смертности не только в основной популяции, но и при хронической болезни почек. Возрастающая распространенность хронической болезни почек и хронической сердечной недостаточности способствует увеличению числа случаев кардиоренального синдрома. Среди методов профилактики и лечения кардиоренального синдрома наряду с применением ингибиторов ангиотензинпревращающего фермента, β-адреноблокаторов, антианемических препаратов и диуретиков актуальны и рекомендуются рядом исследований статины. Использование статинов является эффективной мерой профилактики кардиоренального синдрома у пациентов с высоким риском его развития, улучшает качество жизни и выживаемость, а у додиализных больных с хронической болезнью почек может служить вторичной профилактикой кардиоваскулярной смертности.

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