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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">59</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2012-3-4-67-72</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>PHARMACOTHERAPY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ФАРМАКОТЕРАПИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">RATIONAL THERAPY OF OSTEOARTHRITIS IN OUTPATIENT CONDITIONS</article-title><trans-title-group xml:lang="ru"><trans-title>Рационал ьная терапия остеоартроза в амбулаторных условиях</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Savelova</surname><given-names>E. E.</given-names></name><name xml:lang="ru"><surname>Савелова</surname><given-names>Е. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>savlenaaa@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Maiko</surname><given-names>O. Yu.</given-names></name><name xml:lang="ru"><surname>Майко</surname><given-names>О. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Orenburg State Medical Academy Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Оренбургская государственная медицинская академия» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2012</year></pub-date><volume>6</volume><issue>3-4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>67</fpage><lpage>72</lpage><history><date date-type="received" iso-8601-date="2014-07-15"><day>15</day><month>07</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-07-15"><day>15</day><month>07</month><year>2014</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Savelova E.E., Maiko O.Y.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, Савелова Е.Е., Майко О.Ю.</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Savelova E.E., Maiko O.Y.</copyright-holder><copyright-holder xml:lang="ru">Савелова Е.Е., Майко О.Ю.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/59">https://klinitsist.abvpress.ru/Klin/article/view/59</self-uri><abstract xml:lang="en"><p><bold>Aim.</bold> To evaluate in the comparative aspect of the symptomatic effectiveness of therapy chondroitin sulfate and it’s combination with glucosamine hydrochloride in patients with osteoarthritis in outpatient conditions and determine the most rational scheme of the treatment.</p><p><bold>Materials and methods.</bold> 65 patients with osteoarthritis of the knee and hip joints, of which 35 were chondroitin sulfate and 30 – chondroitin sulfate in combination with glucosamine hydrochloride according to the scheme in the course of 3 months. Additionally carried out x-ray and ultrasound study of the affected joints.</p><p><bold>Results.</bold> The use of these drugs has led to the reduction of pain, the improvement of function of joints and quality of life of patients, whichallowed to reduce the need for receiving nonsteroidal anti-inflammatory drugs.</p><p><bold>Conclusion.</bold> In the outpatient setting can be applied widely chondroitin sulfate in combination with glucosamine hydrochloride, in connection with higher efficiency and lower cost.</p></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="ru"><kwd>остеоартроз</kwd><kwd>хондроитина сульфат</kwd><kwd>глюкозамина гидрохлорид</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Arden N., Nevitt M.C. Osteoarthritis: Epidemiology. 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