The ClinicianThe ClinicianКлиницист1818-83382412-8775Publishing House ABV Press510.17650/1818-8338-2013-3-4-9-13REVIEWОБЗОРINFECTIVE ENDOCARDITIS IN THE PRESENCE OF HYPERTROPHIC CARDIOMYOPATHYИНФЕКЦИОННЫЙ ЭНДОКАРДИТ НА ФОНЕ ГИПЕРТРОФИЧЕСКОЙ КАРДИОМИОПАТИИPonomarevaE. Yu.ПономареваЕ. Ю.
Russian Federation

Department of Hospital Therapy

Кафедра госпитальной терапии лечебного факультета

ponomareva_elena1@mail.ruFaculty of Therapeutics, V.I. Razumovsky Saratov State Medical University, Ministry of Health of RussiaГБОУ ВПО «Саратовский государственный медицинский университет им. В. И. Разумовского» Минздрава России1510201373-49131407201414072014Copyright ©; 2013, Ponomareva E.Y.Copyright ©; 2013, Пономарева Е.Ю.2013Ponomareva E.Y.Пономарева Е.Ю.https://creativecommons.org/licenses/by/4.0https://klinitsist.abvpress.ru/Klin/article/view/5

The paper reviews the literature characterizing the incidence of infective endocarditis (IE) in the presence of hypertrophic cardiomyopathy, as well as hemodynamic mechanisms, etiological features, valvular lesion and the course of IE in this pathology, approaches to treatment and prevention, and outcomes of the disease.

В статье представлен обзор литературы, характеризующий частоту возникновения инфекционного эндокардита (ИЭ) на фоне гипертрофической кардиомиопатии, гемодинамические механизмы, особенности этиологии, клапанного поражения и течения ИЭ при данной патологии, подходы к лечению и профилактике, исходы заболевания.

infective endocarditishypertrophic cardiomyopathyинфекционный эндокардитгипертрофическая кардиомиопатия1. Habib G., Hoen B., Tornos P. et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by theHabib G., Hoen B., Tornos P. et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by theEuropean Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J 2009;30(19):2369–413.2. Виноградова Т. Л. Инфекционный эндокардит: современное течение. Клиницист 2011;(3):4–9.Виноградова Т. Л. Инфекционный эндокардит: современное течение. Клиницист 2011;(3):4–9.3. Moreillon P., Que Y. A. Infective endocarditis. Lancet 2004;363(9403):139–49.Moreillon P., Que Y. A. Infective endocarditis. Lancet 2004;363(9403):139–49.4. Якушин С. С., Филиппов Е. В. Гипертрофическая кардиомиопатия: основы диагностики и лечения. Клиницист 2007;(3):7–14.Якушин С. С., Филиппов Е. В. Гипертрофическая кардиомиопатия: основы диагностики и лечения. Клиницист 2007;(3):7–14.5. Якушин С. С., Филиппов Е. В. Гипертрофическая кардиомиопатия: результаты пятилетнего наблюдения. Болезни сердца и сосудов 2006;2(2):35–40.Якушин С. С., Филиппов Е. В. Гипертрофическая кардиомиопатия: результаты пятилетнего наблюдения. Болезни сердца и сосудов 2006;2(2):35–40.6. Габрусенко С. А. Гипертрофическая кардиомиопатия: современное состояние проблемы. Consilium medicum 2004;6(5):350 –5.Габрусенко С. А. Гипертрофическая кардиомиопатия: современное состояние проблемы. Consilium medicum 2004;6(5):350 –5.7. Maron B. J., McKenna W.J., Danielson G. K. et al. American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of theMaron B. J., McKenna W.J., Danielson G. K. et al. American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of theAmerican College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines. J Am Coll Cardiol 2003;42(9):1687–713.8. Комиссарова С. М., Вайханская Т. Г., Шкет А. П. Диагностика и лечение первичной гипертрофической кардиомиопатии. Национальные рекомендации. Минск:Профессиональные издания, 2010.Комиссарова С. М., Вайханская Т. Г., Шкет А. П. Диагностика и лечение первичной гипертрофической кардиомиопатии. Национальные рекомендации. Минск:Профессиональные издания, 2010.9. Spirito P., Rapezzi C., Bellone P. et al. Infective endocarditis in hypertrophic cardiomyopathy: prevalence, incidence, and indications for antibiotic prophylaxis Circulation 1999;99(16):2132–7.Spirito P., Rapezzi C., Bellone P. et al. Infective endocarditis in hypertrophic cardiomyopathy: prevalence, incidence, and indications for antibiotic prophylaxis Circulation 1999;99(16):2132–7.10. Brusch J. L. Infective Endocarditis. Medscape Reference. Available at: http://emedicine.medscape.com/article/216650-overview/.Brusch J. L. Infective Endocarditis. Medscape Reference. Available at: http://emedicine.medscape.com/article/216650-overview/.11. Morgan-Hughes G., Motwani J. Mitral valve endocarditis in hypertrophic cardiomyopathy: case report and literature review. Heart 2002;87(6):e8.Morgan-Hughes G., Motwani J. Mitral valve endocarditis in hypertrophic cardiomyopathy: case report and literature review. Heart 2002;87(6):e8.12. Louahabi T., Drighil A., Habbal R., Azzouzi L. Infective endocarditis complicating hypertrophic obstructive cardiomyopathy. Eur J Echocardiogr 2006;7(6):468–70.Louahabi T., Drighil A., Habbal R., Azzouzi L. Infective endocarditis complicating hypertrophic obstructive cardiomyopathy. Eur J Echocardiogr 2006;7(6):468–70.13. Тарасова Г. М., Белов Б. С., Балабанова Р. М. Инфекционный эндокардит: ревматологические аспекты. Науч-практ ревматол 2008;(6):11–6.Тарасова Г. М., Белов Б. С., Балабанова Р. М. Инфекционный эндокардит: ревматологические аспекты. Науч-практ ревматол 2008;(6):11–6.14. Alessandri N., Pannarale G., del Monte F. et al. Hypertrophic obstructive cardiomyopathy and infective endocarditis: a report of seven cases and a review of the literature. Eur Heart J 1990;11(11):1041–8.Alessandri N., Pannarale G., del Monte F. et al. Hypertrophic obstructive cardiomyopathy and infective endocarditis: a report of seven cases and a review of the literature. Eur Heart J 1990;11(11):1041–8.15. Богачев Р. С., Базина И. Б., Самородская И. В. Развитие инфекционного эндокардита на фоне гипертрофической кардиомиопатии. Рос кардиол журн 1999;(3):53–5.Богачев Р. С., Базина И. Б., Самородская И. В. Развитие инфекционного эндокардита на фоне гипертрофической кардиомиопатии. Рос кардиол журн 1999;(3):53–5.16. Скопин И. И., Мироненко В. А., Борисов К. В. и др. Хирургическое лечение инфекционного эндокардита митрального клапана у больной с обструктивной формой гипертрофической кардиомиопатии. Анналы хирургии 2008;(1):79–80.Скопин И. И., Мироненко В. А., Борисов К. В. и др. Хирургическое лечение инфекционного эндокардита митрального клапана у больной с обструктивной формой гипертрофической кардиомиопатии. Анналы хирургии 2008;(1):79–80.17. Новиков Ю. И., Полубенцева Е. М., Беспалова Г. Н. Инфекционный эндокардит при гипертрофической кардиомиопатии. Тер архив 1990;62(5):85–9.Новиков Ю. И., Полубенцева Е. М., Беспалова Г. Н. Инфекционный эндокардит при гипертрофической кардиомиопатии. Тер архив 1990;62(5):85–9.18. Chagnac A., Rudniki C., Loebel H., Zahavi I. Infectious endocarditis in idiopathic hypertrophic subaortic stenosis: report of three cases and review of the literature. Chest 1982;81(3):346–9.Chagnac A., Rudniki C., Loebel H., Zahavi I. Infectious endocarditis in idiopathic hypertrophic subaortic stenosis: report of three cases and review of the literature. Chest 1982;81(3):346–9.19. Pachirat O., Klungboonkrong V., Tantisirin C. Infective endocarditis in hypertrophic cardiomyopathy- mural and aortic valve vegetations: a case report.J Med Assoc Thai 2006;89(4):522–6.Pachirat O., Klungboonkrong V., Tantisirin C. Infective endocarditis in hypertrophic cardiomyopathy- mural and aortic valve vegetations: a case report.J Med Assoc Thai 2006;89(4):522–6.20. Wang K., Gobel F. L., Gleason D. F. Bacterial endocarditis in idiopathic hypertrophic subaortic stenosis. Am Heart J 1975;89(3):359–65.Wang K., Gobel F. L., Gleason D. F. Bacterial endocarditis in idiopathic hypertrophic subaortic stenosis. Am Heart J 1975;89(3):359–65.21. Soor G. S., Luk A., Ahn E. et al. Hypertrophic cardiomyopathy: current understanding and treatment objectives. J Clin Pathol 2009;62(3):226–35.Soor G. S., Luk A., Ahn E. et al. Hypertrophic cardiomyopathy: current understanding and treatment objectives. J Clin Pathol 2009;62(3):226–35.22. Roberts W. C., Kishel J. C., McIntosh C.L. et al. Severe mitral or aortic valve regurgitation, or both, requiring valve replacement for infective endocarditis complicating hypertrophic cardiomyopathy. J Am Coll Cardiol 1992;19(2):365–71.Roberts W. C., Kishel J. C., McIntosh C.L. et al. Severe mitral or aortic valve regurgitation, or both, requiring valve replacement for infective endocarditis complicating hypertrophic cardiomyopathy. J Am Coll Cardiol 1992;19(2):365–71.23. Nielsen H. V., Prio T. K. Hypertrophic obstructive cardiomyopathy complicated with bacterial endocarditis. Ugeskr Laeger 1992;154(28):1978–9.Nielsen H. V., Prio T. K. Hypertrophic obstructive cardiomyopathy complicated with bacterial endocarditis. Ugeskr Laeger 1992;154(28):1978–9.24. Ah Fat L. N., Patel B. R., Pickens S. Actinobacillus actinomycetemcomitans endocarditis in hypertrophic obstructive cardiomyopathy. J Infect 1983;6(1):81–4.Ah Fat L. N., Patel B. R., Pickens S. Actinobacillus actinomycetemcomitans endocarditis in hypertrophic obstructive cardiomyopathy. J Infect 1983;6(1):81–4.25. Pitcher D., Mary D. Listeria monocytogenes endocarditis in hypertrophic cardiomyopathy. Br Med J 1978;1(6118):961.Pitcher D., Mary D. Listeria monocytogenes endocarditis in hypertrophic cardiomyopathy. Br Med J 1978;1(6118):961.26. Murdoch D. R., Corey G. R., Hoen B. et al. Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study. Arch Intern Med 2009;169(5):463–73.Murdoch D. R., Corey G. R., Hoen B. et al. Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study. Arch Intern Med 2009;169(5):463–73.27. Olivotto J., Maron M. S., Adabag A. S. et al. Gender-related differences in the clinical presentation and outcome of hypertrophic cardiomyopathy. J Am Coll Cardiol 2005;46(3):480–7.Olivotto J., Maron M. S., Adabag A. S. et al. Gender-related differences in the clinical presentation and outcome of hypertrophic cardiomyopathy. J Am Coll Cardiol 2005;46(3):480–7.28. Aksoy O., Meyer L., Cabell C. et al. Gender differences in infective endocarditis: pre- and co-morbid conditions lead to different management and outcomes in female patients. Scand J Infect Dis 2007;39(2):101–7.Aksoy O., Meyer L., Cabell C. et al. Gender differences in infective endocarditis: pre- and co-morbid conditions lead to different management and outcomes in female patients. Scand J Infect Dis 2007;39(2):101–7.29. Демин А. А., Демин Ал. А. Бактериальные эндокардиты. М.: Медицина, 1978.Демин А. А., Демин Ал. А. Бактериальные эндокардиты. М.: Медицина, 1978.30. Буткевич О. М., Виноградова Т. Л. О трудностях диагностики инфекционного эндокардита современного течения. Тер архив 1996;68(8):21–4.Буткевич О. М., Виноградова Т. Л. О трудностях диагностики инфекционного эндокардита современного течения. Тер архив 1996;68(8):21–4.31. Поляков В. П., Николаевский Е. Н., Хубулава Г. Г. и др. Инфекционный эндокардит (современное состояние проблемы). Самара, 2006.Поляков В. П., Николаевский Е. Н., Хубулава Г. Г. и др. Инфекционный эндокардит (современное состояние проблемы). Самара, 2006.32. Чипигина Н. С., Озерецкий К. С. Инфекционный эндокардит: внесердечные клинические проявления. Сердце 2003;2(5):231–5.Чипигина Н. С., Озерецкий К. С. Инфекционный эндокардит: внесердечные клинические проявления. Сердце 2003;2(5):231–5.33. Inoue T., Shinohara T., Sаqа T. Surgical treatment of infective endocarditis complicated by intracranial hemorrhage in a patient with hypertrophic obstructive cardiomyopathy. Can J Cardiol 2004;20(6):643–5.Inoue T., Shinohara T., Sаqа T. Surgical treatment of infective endocarditis complicated by intracranial hemorrhage in a patient with hypertrophic obstructive cardiomyopathy. Can J Cardiol 2004;20(6):643–5.34. Furlan A. J., Craciun A. R., Raju N. R., Hart N. Cerebrovascular complications associated with idiopathic hypertrophic subaortic stenosis. Stroke 1984;15(2):282–4.Furlan A. J., Craciun A. R., Raju N. R., Hart N. Cerebrovascular complications associated with idiopathic hypertrophic subaortic stenosis. Stroke 1984;15(2):282–4.35. McKenna W.J., England D., Doi Y. L. et al. Arrhythmia in hypertrophic cardiomyopathy. I: Influence on prognosis. Br Heart J 1981;46(2):168–72.McKenna W.J., England D., Doi Y. L. et al. Arrhythmia in hypertrophic cardiomyopathy. I: Influence on prognosis. Br Heart J 1981;46(2):168–72.36. Амосова Е. Н. Кардиомиопатии. Киев: Книга плюс, 1999.Амосова Е. Н. Кардиомиопатии. Киев: Книга плюс, 1999.37. Morrow A. G., Reitz B. A., Epstein S. E. et al. Operative treatment in hypertrophic subaortic stenosis. Techniques, and the results of pre and postoperative assessments in 83 patients. Circulation 1975;52(1):88–102.Morrow A. G., Reitz B. A., Epstein S. E. et al. Operative treatment in hypertrophic subaortic stenosis. Techniques, and the results of pre and postoperative assessments in 83 patients. Circulation 1975;52(1):88–102.38. Heric B., Lytle B. W., Miller D. P. et al. Surgical management of hypertrophic obstructive cardiomyopathy: early and late results. J Thorac Cardiovasc Surg 1995;110(1):195–206.Heric B., Lytle B. W., Miller D. P. et al. Surgical management of hypertrophic obstructive cardiomyopathy: early and late results. J Thorac Cardiovasc Surg 1995;110(1):195–206.39. Zemanek D., Veselka J., Chmelovа R. Infective endocarditis after alcohol septal ablation for obstructive hypertrophic cardiomyopathy. Int Heart J 2008;49(3):371–5.Zemanek D., Veselka J., Chmelovа R. Infective endocarditis after alcohol septal ablation for obstructive hypertrophic cardiomyopathy. Int Heart J 2008;49(3):371–5.40. Nogami A., Fujiwara T., Masaki H. et al. A case of hypertrophic obstructive cardiomyopathy (HOCM) complicated by infective endocarditis (IE) and mitral regurgitation (MR) [Article in Japanese]. Kyobu Geka 1994;47(6):470–3.Nogami A., Fujiwara T., Masaki H. et al. A case of hypertrophic obstructive cardiomyopathy (HOCM) complicated by infective endocarditis (IE) and mitral regurgitation (MR) [Article in Japanese]. Kyobu Geka 1994;47(6):470–3.41. Horstkotte D., Follath F., Gutschik E. et al. Guidelines on prevention, diagnosis and treatment of infective endocarditis executive summary; the task force on infective endocarditis of the European society of cardiology. Eur Heart J 2004;25(3):267–76.Horstkotte D., Follath F., Gutschik E. et al. Guidelines on prevention, diagnosis and treatment of infective endocarditis executive summary; the task force on infective endocarditis of the European society of cardiology. Eur Heart J 2004;25(3):267–76.42. Bach D. S.; American College of Cardiology/American Heart Association. Perspectives on the American College of Cardiology/American Heart Association guidelines for the prevention of infective endocarditis. J Am Coll Cardiol 2009;53(20):1852–4.Bach D. S.; American College of Cardiology/American Heart Association. Perspectives on the American College of Cardiology/American Heart Association guidelines for the prevention of infective endocarditis. J Am Coll Cardiol 2009;53(20):1852–4.43. Wilson W., Taubert K. A., Gewitz M. et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 2007;116(15):1736–54.Wilson W., Taubert K. A., Gewitz M. et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 2007;116(15):1736–54.44. Nishimura R. A., Carabello B. A., Faxon D. P. et al. ACC/AHA 2008 Guideline update on valvular heart disease: focused update on infective endocarditis: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol 2008;52(8):676–85.Nishimura R. A., Carabello B. A., Faxon D. P. et al. ACC/AHA 2008 Guideline update on valvular heart disease: focused update on infective endocarditis: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol 2008;52(8):676–85.45. Maron B. J., Lever H. In defense of antimicrobial prophylaxis for prevention of infective endocarditis in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 2009;54(24):2339–40.Maron B. J., Lever H. In defense of antimicrobial prophylaxis for prevention of infective endocarditis in patients with hypertrophic cardiomyopathy. J Am Coll Cardiol 2009;54(24):2339–40.46. Белов Б. С. Профилактика инфекционного эндокардита: современные аспекты. Consilium medicum 2008;10(1):79–85.Белов Б. С. Профилактика инфекционного эндокардита: современные аспекты. Consilium medicum 2008;10(1):79–85.47. Swan D. A., Bell B., Oakley C., Goodwin J. Analysis of symptomatic course and prognosis and treatment of hypertrophic obstructive cardiomyopathy. Br Heart J 1971;33(5):671–85.Swan D. A., Bell B., Oakley C., Goodwin J. Analysis of symptomatic course and prognosis and treatment of hypertrophic obstructive cardiomyopathy. Br Heart J 1971;33(5):671–85.48. de Castro S., Adorisio R., Pelliccia A. et al. Perforated aneurysms of left side valves during active infective endocarditis complicating hypertrophic obstructive cardiomyopathy. Eur J Echocardiogr 2002;3(2):100–2.de Castro S., Adorisio R., Pelliccia A. et al. Perforated aneurysms of left side valves during active infective endocarditis complicating hypertrophic obstructive cardiomyopathy. Eur J Echocardiogr 2002;3(2):100–2.