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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">49</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2012-6-3-4-</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Role of the new cytokines growth differentiation factor 15 (GDF-15) and cartilage glycoprotein 39 (YKL-40) in the development and progression of coronary artery atherosclerosis</article-title><trans-title-group xml:lang="ru"><trans-title>Роль новых цитокинов : ростового фактора дифференцировки 15 (GDF-15) и хрящевого гликопротеина 39 (YKL-40) в развитии и прогрессировании атеросклероза коронарных артерий</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Еzhov</surname><given-names>M. V.</given-names></name><name xml:lang="ru"><surname>Ежов</surname><given-names>М. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Atherosclerosis Problems</p></bio><bio xml:lang="ru"><p>Отдел проблем атеросклероза Института клинической кардиологии им. А.Л. Мясникова</p></bio><email>marat_ezhov@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Polevaya</surname><given-names>T. Yu.</given-names></name><name xml:lang="ru"><surname>Полевая</surname><given-names>Т. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Atherosclerosis Problems</p></bio><bio xml:lang="ru"><p>Отдел проблем атеросклероза Института клинической кардиологии им. А.Л. Мясникова</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Matchin</surname><given-names>Yu. G.</given-names></name><name xml:lang="ru"><surname>Матчин</surname><given-names>Ю. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Atherosclerosis Problems</p></bio><bio xml:lang="ru"><p>Отдел проблем атеросклероза Института клинической кардиологии им. А.Л. Мясникова</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">A.L. Myasnikov Institute of Clinical Cardiology&#13;
&#13;
Russian Cardiology Research-and-Production Complex, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Российский кардиологический научно-производственный комплекс» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2012-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2012</year></pub-date><volume>6</volume><issue>3-4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>17</fpage><lpage>22</lpage><history><date date-type="received" iso-8601-date="2014-07-15"><day>15</day><month>07</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-07-15"><day>15</day><month>07</month><year>2014</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Еzhov M.V., Polevaya T.Y., Matchin Y.G.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, Ежов М.В., Полевая Т.Ю., Матчин Ю.Г.</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Еzhov M.V., Polevaya T.Y., Matchin Y.G.</copyright-holder><copyright-holder xml:lang="ru">Ежов М.В., Полевая Т.Ю., Матчин Ю.Г.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/49">https://klinitsist.abvpress.ru/Klin/article/view/49</self-uri><abstract xml:lang="en"><p>The review presents new data of studying the nonspecific biomarkers belonging to the family of cytokines: cartilage glycoprotein 39 and growth differentiation factor 15 in coronary atherosclerosis.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре представлены новые данные по изучению неспецифических биомаркеров, относящихся к семейству цитокинов: хрящевого гликопротеина 39 и ростового фактора дифференцировки 15, при коронарном атеросклерозе.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cytokines</kwd><kwd>coronary atherosclerosis</kwd><kwd>growth differentiation factor 15</kwd><kwd>cartilage glycoprotein 39</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>цитокины</kwd><kwd>коронарный атеросклероз</kwd><kwd>ростовой фактор дифференцировки 15</kwd><kwd>хрящевой гликопротеин 39</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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