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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">388</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2019-13-1-2-65-71</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CASE REPORT</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОПИСАНИЕ СЛУЧАЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Primary infective endocarditis with isolated involvement of the pulmonary valve not associated with drug addiction</article-title><trans-title-group xml:lang="ru"><trans-title>Первичный инфекционный эндокардит c изолированным поражением клапана легочной артерии, не связанный с наркоманией</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2083-0437</contrib-id><name-alternatives><name xml:lang="en"><surname>Chipigina</surname><given-names>N. S.</given-names></name><name xml:lang="ru"><surname>Чипигина</surname><given-names>Н. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Ostrovityanova St., Moscow 117997, Russia</p></bio><bio xml:lang="ru"><p>Россия, 117997 Москва, ул. Островитянова, 1</p></bio><email>chipigina-natalia56@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7841-8966</contrib-id><name-alternatives><name xml:lang="en"><surname>Karpova</surname><given-names>N. Yu.</given-names></name><name xml:lang="ru"><surname>Карпова</surname><given-names>Н. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Ostrovityanova St., Moscow 117997, Russia</p></bio><bio xml:lang="ru"><p>Россия, 117997 Москва, ул. Островитянова, 1</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tulinov</surname><given-names>M. M.</given-names></name><name xml:lang="ru"><surname>Тулинов</surname><given-names>М. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>18 A Zagorodnoe Highway, Moscow 117152, Russia</p></bio><bio xml:lang="ru"><p>Россия, 117152 Москва, Загородное шоссе, 18А</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Golovko</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Головко</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>18 A Zagorodnoe Highway, Moscow 117152, Russia</p></bio><bio xml:lang="ru"><p>Россия, 117152 Москва, Загородное шоссе, 18А</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Goloukhova</surname><given-names>L. M.</given-names></name><name xml:lang="ru"><surname>Голоухова</surname><given-names>Л. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>18 A Zagorodnoe Highway, Moscow 117152, Russia</p></bio><bio xml:lang="ru"><p>Россия, 117152 Москва, Загородное шоссе, 18А</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kornienko</surname><given-names>V. S.</given-names></name><name xml:lang="ru"><surname>Корниенко</surname><given-names>В. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>18 A Zagorodnoe Highway, Moscow 117152, Russia</p></bio><bio xml:lang="ru"><p>Россия, 117152 Москва, Загородное шоссе, 18А</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kostin</surname><given-names>A. Yu.</given-names></name><name xml:lang="ru"><surname>Костин</surname><given-names>А. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>18 A Zagorodnoe Highway, Moscow 117152, Russia</p></bio><bio xml:lang="ru"><p>Россия, 117152 Москва, Загородное шоссе, 18А</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0592-3181</contrib-id><name-alternatives><name xml:lang="en"><surname>Barsegyan</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Барсегян</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Ostrovityanova St., Moscow 117997, Russia</p></bio><bio xml:lang="ru"><p>Россия, 117997 Москва, ул. Островитянова, 1</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Pirogov National Research Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н. И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">City Clinical Oncological Hospital No. 1 of the Moscow Healthcare Department, branch No. 1</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Городская клиническая онкологическая больница № 1 Департамента здравоохранения г. Москвы», филиал № 1</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2019</year></pub-date><volume>13</volume><issue>1-2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>65</fpage><lpage>71</lpage><history><date date-type="received" iso-8601-date="2019-08-24"><day>24</day><month>08</month><year>2019</year></date><date date-type="accepted" iso-8601-date="2019-08-24"><day>24</day><month>08</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Chipigina N.S., Karpova N.Y., Tulinov M.M., Golovko E.V., Goloukhova L.M., Kornienko V.S., Kostin A.Y., Barsegyan V.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, Чипигина Н.С., Карпова Н.Ю., Тулинов М.М., Головко Е.В., Голоухова Л.М., Корниенко В.С., Костин А.Ю., Барсегян В.А.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Chipigina N.S., Karpova N.Y., Tulinov M.M., Golovko E.V., Goloukhova L.M., Kornienko V.S., Kostin A.Y., Barsegyan V.A.</copyright-holder><copyright-holder xml:lang="ru">Чипигина Н.С., Карпова Н.Ю., Тулинов М.М., Головко Е.В., Голоухова Л.М., Корниенко В.С., Костин А.Ю., Барсегян В.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/388">https://klinitsist.abvpress.ru/Klin/article/view/388</self-uri><abstract xml:lang="en"><p><bold>Objective: </bold>to describe a rare case of infective endocarditis (IE) with isolated localization in the pulmonary valve (PV).</p><p><bold>Materials and methods. </bold>We observed primary IE with isolated localization in the PV in a 27-year-old female patient without risk factors of right-side IE.</p><p><bold>Results. </bold>The disease was caused by Streptococcus gordonii and proceeded acutely with typical signs of right-side IE: fever above 38 °С, chills, clinical picture of bilateral septic embolic abscess pneumonia, as well as secondary anemia, secondary thrombocytopenia, and glomerulonephritis. Echocardiography showed large vegetations in the PV prolapsing in the right ventricle and pulmonary artery.</p><p><bold>Conclusion. </bold>IE with localization in the PV should be suspected in patients with fever and clinical picture of septic embolic pneumonia in absence of other embolic situations.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель исследования </bold>– описать редкий случай инфекционного эндокардита (ИЭ) с изолированной локализацией на клапане легочной артерии (ЛА).</p><p><bold>Материалы и методы</bold>. Мы наблюдали первичный ИЭ с изолированной локализацией на клапане ЛА у 27-летней больной без факторов риска ИЭ правых отделов сердца.</p><p><bold>Результаты. </bold>Заболевание было вызвано Streptococcus gordonii и протекало остро с типичными проявлениями ИЭ правых отделов сердца: лихорадкой выше 38 °С, ознобами, клинической картиной двусторонней септической эмбологенной абсцедирующей пневмонии, а также вторичной анемией, вторичной тромбоцитопенией и гломерулонефритом. При эхокардиографическом исследовании были выявлены крупные вегетации на клапане ЛА, пролабирующие в правый желудочек и ЛА.</p><p><bold>Заключение. </bold>ИЭ с локализацией на клапане ЛА следует предполагать у лихорадящих пациентов с клинической картиной септической эмбологенной пневмонии при отсутствии других эмбологенных ситуаций.</p></trans-abstract><kwd-group xml:lang="en"><kwd>infective endocarditis of the pulmonary valve</kwd><kwd>right-side infective endocarditis</kwd><kwd>infective endocarditis risk factors</kwd><kwd>primary infective endocarditis</kwd><kwd>secondary septic infective endocarditis</kwd><kwd>embolic pneumonia</kwd><kwd>Streptococcus gordonii</kwd><kwd>alpha-hemolytic streptococcus</kwd><kwd>congenital heart disease</kwd><kwd>glomerulonephritis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>инфекционный эндокардит клапана легочной артерии</kwd><kwd>инфекционный эндокардит правых отделов сердца</kwd><kwd>факторы риска инфекционного эндокардита</kwd><kwd>первичный инфекционный эндокардит</kwd><kwd>вторичный септический инфекционный эндокардит</kwd><kwd>эмбологенная пневмония</kwd><kwd>Streptococcus gordonii</kwd><kwd>зеленящий стрептококк</kwd><kwd>врожденный порок сердца</kwd><kwd>гломерулонефрит</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Park L. 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