The ClinicianThe ClinicianКлиницист1818-83382412-8775Publishing House ABV Press3710.17650/1818-8338-2013-1-14-20REVIEWОБЗОРCYTOPROTECTIVE AND NEUROTROPHIC THERAPY FOR CEREBRAL STROKEЦИТОПРОТЕКТИВНАЯ И НЕЙРОТРОФИЧЕСКАЯ ТЕРАПИЯ ПРИ ЦЕРЕБРАЛЬНОМ ИНСУЛЬТЕMartynovM. Yu.МартыновМ. Ю.
Russian Federation
m-martin@inbox.ruYasamanovaA. N.ЯсамановаА. Н.
Russian Federation
ShchukinI. A.ЩукинИ. А.
Russian Federation
KolesnikovaT. I.КолесниковаТ. И.
Russian Federation
ChubykinV. I.ЧубыкинВ. И.
Russian Federation
N.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaГБОУ ВПО РНИМУ им. Н.И. Пирогова Минздрава России150120137114201507201415072014Copyright ©; 2013, Martynov M.Y., Yasamanova A.N., Shchukin I.A., Kolesnikova T.I., Chubykin V.I.Copyright ©; 2013, Мартынов М.Ю., Ясаманова А.Н., Щукин И.А., Колесникова Т.И., Чубыкин В.И.2013Martynov M.Y., Yasamanova A.N., Shchukin I.A., Kolesnikova T.I., Chubykin V.I.Мартынов М.Ю., Ясаманова А.Н., Щукин И.А., Колесникова Т.И., Чубыкин В.И.https://creativecommons.org/licenses/by/4.0https://klinitsist.abvpress.ru/Klin/article/view/37

The paper gives the data of Russian and foreign studies on the pathophysiological mechanisms of brain injury in ischemic and hemorrhagicstroke, the specific features of brain plasticity and its activation after cerebral stroke, and main directions for basic and differentiation therapy for acute cerebrovascular pathology. Particular emphasis is placed on the issues of cytoprotective and neurotrophic therapy for cerebral stroke. Analysis of the data available in the literature shows that cytoprotective and neurotrophic therapies are important components of combination treatment in patients with stroke and favorably affect the functional outcome of the disease.

В статье приведены данные отечественных и зарубежных исследований, затрагивающие патофизиологические механизмы повреждения головного мозга при ишемическом и геморрагическом инсульте, особенности пластичности в головном мозге и ее активизации после церебрального инсульта, основные направления базисной и дифференцированной терапии острой цереброваскулярной патологии. Особое внимание уделено рассмотрению вопросов проведения цитопротективной и нейротрофической терапии при церебральном инсульте. На основании анализа литературных данных показано, что цитопротективная и нейротрофическая терапия являются важными составляющими комплексного лечения больных с инсультом и позволяют благоприятно влиять на функциональный исход заболевания.

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