The ClinicianThe ClinicianКлиницист1818-83382412-8775Publishing House ABV Press3410.17650/1818-8338-2013-2-88-93PHARMACOTHERAPYФАРМАКОТЕРАПИЯCEREBROVASCULAR DISEASES: THE POSSIBILITIES AND EFFICIENCY OF METABOLIC THERAPYЦереброваскулярные заболевания : возможности и эффективност ь метаболической терапииUmarovaKh. Ya.УмароваХ. Я.
Russian Federation

Medical Faculty

Медицинский факультет

khadi700@mail.ruKazakovA. Yu.КазаковА. Ю.
Russian Federation
ChugunovA. V.ЧугуновА. В.
Russian Federation
MakeevaM. M.МакееваМ. М.
Russian Federation
Chechen State UniversityФГБОУ ВПО «Чеченский государственный университет», ГрозныйN.I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaГБОУ ВПО РНИМУ им. Н.И. Пирогова Минздрава РоссииCity Polyclinic ThreeГБУЗ «Городская поликлиника № 3»150420137288931507201415072014Copyright ©; 2013, Umarova K.Y., Kazakov A.Y., Chugunov A.V., Makeeva M.M.Copyright ©; 2013, Умарова Х.Я., Казаков А.Ю., Чугунов А.В., Макеева М.М.2013Umarova K.Y., Kazakov A.Y., Chugunov A.V., Makeeva M.M.Умарова Х.Я., Казаков А.Ю., Чугунов А.В., Макеева М.М.https://creativecommons.org/licenses/by/4.0https://klinitsist.abvpress.ru/Klin/article/view/34

Acute and chronic brain ischemia is accompanied by complex metabolic rearrangements in the neurons. The ability of the cells to survive is largely determined by the presence of energy substrates and oxygen, the synthesis of neurotransmitters, and some other factors. The increasedpersistence of nerve tissue in ischemia and chances of recovering the impaired function can be achieved by the use of neuroprotective and neurotrophic agents. The efficiency of neurometabolic therapy is considered using Ceraxon and Actovegin as an example. It is emphasized that theefficiency of their administration can be achieved by the mandatory concurrent use of a wide range of nondrug treatments.

Острая и хроническая ишемия головного мозга сопровождаются сложной перестройкой метаболизма нейронов. Способность клеток к выживанию в значительной степени определяется наличием энергетических субстратов, кислорода, синтезом нейротрансмиттеров и некоторыми другими факторами. Повышение сохранности нервной ткани в условиях ишемии, возможность восстановления нарушенных функций могут достигаться применением препаратов нейропротекторного и нейротрофического действия. Эффективность нейрометаболической терапии рассматривается на примере препаратов Цераксон и Актовегин. Подчеркивается, что достижение эффективности их применения возможно при обязательном одновременном использованииширокого спектра немедикаментозных способов лечения.

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