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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">311</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2017-11-2-49-57</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">GENDER-RELATED CHARACTERISTICS OF AFFECTIVE DISORDERS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION</article-title><trans-title-group xml:lang="ru"><trans-title>ГЕНДЕРНЫЕ ОСОБЕННОСТИ АФФЕКТИВНЫХ РАССТРОЙСТВ У БОЛЬНЫХ ОСТРЫМ ИНФАРКТОМ МИОКАРДА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mukhtarenko</surname><given-names>S. Yu.</given-names></name><name xml:lang="ru"><surname>Мухтаренко</surname><given-names>С. Ю.</given-names></name></name-alternatives><address><country country="KG">Kyrgyzstan</country></address><bio xml:lang="en"><p>3 Togolok Moldo St., Bishkek 720040.</p></bio><bio xml:lang="ru"><p>720040 Бишкек, ул. Тоголок Молдо, 3.</p></bio><email>muhtarenko@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Murataliev</surname><given-names>T. M.</given-names></name><name xml:lang="ru"><surname>Мураталиев</surname><given-names>Т. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 Togolok Moldo St., Bishkek 720040.</p></bio><bio xml:lang="ru"><p>720040 Бишкек, ул. Тоголок Молдо, 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nekludova</surname><given-names>Yu. N.</given-names></name><name xml:lang="ru"><surname>Неклюдова</surname><given-names>Ю. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 Togolok Moldo St., Bishkek 720040.</p></bio><bio xml:lang="ru"><p>720040 Бишкек, ул. Тоголок Молдо, 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Radzhapova</surname><given-names>Z. T.</given-names></name><name xml:lang="ru"><surname>Раджапова</surname><given-names>З. Т.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>44 Kievskaya St., Bishkek 720000.</p></bio><bio xml:lang="ru"><p>720000 Бишкек, ул. Киевская, 44.</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zventsova</surname><given-names>V. K.</given-names></name><name xml:lang="ru"><surname>Звенцова</surname><given-names>В. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 Togolok Moldo St., Bishkek 720040.</p></bio><bio xml:lang="ru"><p>720040 Бишкек, ул. Тоголок Молдо, 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Center of Cardiology and Therapy named after academician Mirsaid Mirrakhimov under the Ministry  of Health of the Kyrgyz Republic.</institution></aff><aff><institution xml:lang="ru">Национальный центр кардиологии и терапии им. акад. Мирсаида Миррахимова при Министерстве здравоохранения Кыргызской Республики.</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Kyrgyz-Russian Slavic University named after the First President of Russia B.N. Yeltsin.</institution></aff><aff><institution xml:lang="ru">Кыргызско-Российский Славянский университет им. первого Президента России Б.Н. Ельцина.</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2017</year></pub-date><volume>11</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>49</fpage><lpage>57</lpage><history><date date-type="received" iso-8601-date="2017-12-19"><day>19</day><month>12</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-12-19"><day>19</day><month>12</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Mukhtarenko S.Y., Murataliev T.M., Nekludova Y.N., Radzhapova Z.T., Zventsova V.K.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Мухтаренко С.Ю., Мураталиев Т.М., Неклюдова Ю.Н., Раджапова З.Т., Звенцова В.К.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Mukhtarenko S.Y., Murataliev T.M., Nekludova Y.N., Radzhapova Z.T., Zventsova V.K.</copyright-holder><copyright-holder xml:lang="ru">Мухтаренко С.Ю., Мураталиев Т.М., Неклюдова Ю.Н., Раджапова З.Т., Звенцова В.К.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/311">https://klinitsist.abvpress.ru/Klin/article/view/311</self-uri><abstract xml:lang="en"><p><bold>The study objective</bold> is to investigate characteristics of mixed anxiety-depressive disorders (MADD) and the level of subjective self-control  in relation to health (SSCh), as well as the effect of affective disorder severity on clinical course and prognosis of the disease in men and women with acute myocardial infarction (AMI).</p><p><bold>Materials and methods.</bold> The study included 124 patients with AMI aged between 30 and 85 years (mean age 58.6  ±  12.1 years), who were divided into 2 groups: the 1st group contained 88 (71 %) men, the 2nd group – 36 (29 %) women.</p><p><bold>Results.</bold> Per the screening test, MADD was more frequently diagnosed in the female group (91.7 %) compared to the male group (56.8 %),  р &lt;0.001. Absence of anxiety symptoms per the Hospital Anxiety and Depression Scale (HADS) was more frequently observed in the male group (77.3 % vs. 52.8 %, р &lt;0.01; relative risk (RR) 1.46; 95 % confidence interval (CI) 1.05–2.03), and significant level of anxiety per HADS was more frequently diagnosed in the female group (4.5 % vs. 27.8 %, р &lt;0.01; RR 0.16; 95 % CI 0.05–0.48). Absence of depression symptoms per HADS was more frequently observed in the male group (68.2 % vs. 30.6 %, р &lt;0.01; RR 2.23; 95 % CI 1.33–3.72), and moderate (14.8 % vs. 33.3 %, р &lt;0.05; RR 0.44; 95 % CI 0.22–0.87) and severe (17.0 % vs. 36.1 %, р &lt;0.05; RR 0.47; 95 % CI 0.25– 0.88) levels of depression per HADS were more common in the female group. Absence of depression symptoms per the Beck Depression Inventory (BDI) was more frequently observed in the male group (42.1 % vs. 11.1 % women, р &lt;0.01; RR 3.78; 95 % CI 1.45–9.84). In the female group, moderate (27.8 % vs. 10.2 %, р &lt;0.05; RR 0.36; 95 % CI 0.16–0.83) and severe (13.9 % vs. 3.4 %, р &lt;0.05; RR 0.24; 95 % CI 0.06–0.97) levels of depression per this scale were more common than in the male group. Left ventricular ejection fraction was lower  in the female group (41.4 ± 11.4 %) compared to the male group (45.8 ± 10.3 %), р &lt;0.05. Mortality was higher in the female group compared to the male group: overall (19.4 % vs. 5.7 %, р &lt;0.05), hospital (8.3 % vs. 1.1 %, р &lt;0.05), and post-hospital (11.1 % vs. 4.5 %,  р &gt;0.05) mortality, respectively. </p><p><bold>Conclusion.</bold> Psychometric tests have shown higher rate and severity of MADD in the female group compared to the male group. In the female group, left ventricular ejection fraction was significantly lower than in the male group, and overall and hospital mortality was higher. </p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель исследования</bold> – изучить особенности тревожно-депрессивных расстройств (ТДР) и уровня субъективного контроля личности в отношении здоровья (УСКз), а также влияние выраженности аффективных расстройств на клиническое течение и прогноз заболевания у мужчин и женщин с острым инфарктом миокарда.</p><p><bold>Материалы и методы.</bold> В исследование были включены 124 больных с острым инфарктом миокарда в возрасте от 30 до 85 лет (средний возраст 58,6 ± 12,1 года), которые были разделены на 2 группы: 1-я группа – 88 (71 %) мужчин, 2-я группа – 36 (29 %) женщин.</p><p><bold>Результаты.</bold> ТДР по скрининговому опроснику диагностировались чаще в группе женщин (91,7 %) по сравнению с группой мужчин (56,8 %), р &lt;0,001. Отсутствие симптомов тревоги по госпитальной шкале тревоги и депрессии (HADS) чаще отмечалось в группе мужчин (77,3 % против 52,8 %, р &lt;0,01; отношение рисков (ОР) 1,46; 95 % доверительный интервал (ДИ) 1,05–2,03), а выраженная степень тревоги по HADS диагностировалась чаще в группе женщин (27,8 % против 4,5 %, р &lt;0,01; ОР 0,16; 95 % ДИ 0,05–0,48). Отсутствие симптомов депрессии по HADS чаще отмечалось в группе мужчин (68,2 % против 30,6 %, р &lt;0,01; ОР 2,23; 95 % ДИ 1,33–3,72), а умеренная (14,8 % против 33,3 %, р &lt;0,05; ОР 0,44; 95 % ДИ 0,22–0,87) и выраженная (17,0 % против 36,1 %, р &lt;0,05; ОР 0,47; 95 % ДИ 0,25–0,88) степени депрессии по HADS чаще встречались в группе женщин. Отсутствие симптомов депрессии по шкале депрессии Бека (BDI) отмечалось чаще в группе мужчин (42,1 % против 11,1 % женщин, р &lt;0,01; ОР 3,78; 95 % ДИ 1,45–9,84). В группе женщин чаще встречалась умеренная (27,8 % против 10,2 %, р &lt;0,05; ОР 0,36; 95 % ДИ 0,16–0,83) и тяжелая (13,9 % против 3,4 %, р &lt;0,05; ОР 0,24; 95 % ДИ 0,06–0,97) степени депрессии по этой шкале. Показатель фракции выброса левого желудочка был ниже в группе женщин (41,4 ± 11,4 %) по сравнению с группой мужчин (45,8 ± 10,3 %),  р &lt;0,05. Летальность была выше в группе женщин по сравнению с таковой в группе мужчин: общая летальность (19,4 % против 5,7 %, р &lt;0,05), госпитальная (8,3 % против 1,1 %, р &lt;0,05) и постгоспитальная (11,1 % против 4,5 %, р &gt;0,05) соответственно.</p><p><bold>Заключение.</bold> По данным обследования психометрическими тестами отмечалась бóльшая частота встречаемости и выраженности ТДР в группе женщин по сравнению с группой мужчин. В группе женщин показатель фракции выброса левого желудочка был значимо ниже по сравнению с таковым в группе мужчин, а частота общей и госпитальной летальности у них была выше.</p></trans-abstract><kwd-group xml:lang="en"><kwd>acute myocardial infarction</kwd><kwd>affective disorders</kwd><kwd>anxiety</kwd><kwd>depression</kwd><kwd>gender-related characteristics</kwd><kwd>level of subjective selfcontrol in relation to health</kwd><kwd>HADS</kwd><kwd>BDI</kwd><kwd>left ventricular ejection fraction</kwd><kwd>prognosis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>острый инфаркт миокарда</kwd><kwd>аффективные расстройства</kwd><kwd>тревога</kwd><kwd>депрессия</kwd><kwd>гендерные особенности</kwd><kwd>уровень субъективного контроля личности в отношении здоровья</kwd><kwd>HADS</kwd><kwd>BDI</kwd><kwd>фракция выброса левого желудочка</kwd><kwd>прогноз</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Здоровье населения и деятельность организаций здравоохранения Кыргызской Республики в 2015 году. 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