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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">31</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2013-2-64-72</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>LECTION</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ЛЕКЦИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">ASTHENIA IN PATIENTS WITH CHRONIC NEUROLOGICAL DISEASES</article-title><trans-title-group xml:lang="ru"><trans-title>Астения у пациентов с хроническими неврологическими заболеваниями</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shchukin</surname><given-names>I. A.</given-names></name><name xml:lang="ru"><surname>Щукин</surname><given-names>И. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>ivashchukin@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lebedeva</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Лебедева</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chubykin</surname><given-names>V. I.</given-names></name><name xml:lang="ru"><surname>Чубыкин</surname><given-names>В. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sorokoletov</surname><given-names>S. M.</given-names></name><name xml:lang="ru"><surname>Сороколетов</surname><given-names>С. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Soldatov</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Солдатов</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia&#13;
&#13;
N.I. Pirogov City Clinical Hospital Оne, Moscow Healthcare Departmen</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО РНИМУ им. Н.И. Пирогова Минздрава России&#13;
&#13;
ГБУЗ «Городская клиническая больница № 1 им. Н.И. Пирогова» Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.I. Pirogov City Clinical Hospital Оne, Moscow Healthcare Departmen</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Городская клиническая больница № 1 им. Н.И. Пирогова» Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2013</year></pub-date><volume>7</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>64</fpage><lpage>72</lpage><history><date date-type="received" iso-8601-date="2014-07-14"><day>14</day><month>07</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-07-14"><day>14</day><month>07</month><year>2014</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Shchukin I.A., Lebedeva A.V., Chubykin V.I., Sorokoletov S.M., Soldatov M.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Щукин И.А., Лебедева А.В., Чубыкин В.И., Сороколетов С.М., Солдатов М.А.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Shchukin I.A., Lebedeva A.V., Chubykin V.I., Sorokoletov S.M., Soldatov M.A.</copyright-holder><copyright-holder xml:lang="ru">Щукин И.А., Лебедева А.В., Чубыкин В.И., Сороколетов С.М., Солдатов М.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/31">https://klinitsist.abvpress.ru/Klin/article/view/31</self-uri><abstract xml:lang="en"><p>The paper considers the basic mechanisms for the occurrence of asthenic syndrome in chronic neurological diseases. It shows the significance ofthis problem in nosological entities, such as stroke sequels, multiple sclerosis, and Parkinson’s disease. The main asthenia diagnostic scales aredescribed. Possible therapeutic strategies aimed at reducing the degree of asthenia in neurological patients are also presented.</p></abstract><trans-abstract xml:lang="ru"><p>В статье рассмотрены основные механизмы возникновения астенического синдрома при хронических неврологических заболеваниях. Показана значимость данной проблемы при таких нозологиях, как последствия острых нарушений мозгового кровообращения, рассеянный склероз и болезнь Паркинсона. Описаны основные диагностические шкалы для оценки астении. Также представлены возможные терапевтические стратегии, направленные на уменьшение выраженности астении у неврологических пациентов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>asthenia</kwd><kwd>stroke</kwd><kwd>multiple sclerosis</kwd><kwd>Parkinson’s disease</kwd><kwd>idebenone</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>астения</kwd><kwd>инсульт</kwd><kwd>рассеянный склероз</kwd><kwd>болезнь Паркинсона</kwd><kwd>идебенон</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Zwarts M.J., Bleijenberg G., van Engelen B.G. Clinical neurophysiology of fatigue. Clin Neurophysiol</mixed-citation><mixed-citation xml:lang="ru">Zwarts M.J., Bleijenberg G., van Engelen B.G. Clinical neurophysiology of fatigue. 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