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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">306</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2017-11-2-10-15</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>EDITORIAL</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>РЕДАКЦИОННАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">ANTITHROMBOTIC THERAPY IN PATIENTS WITH VALVULAR HEART DISEASE: WHAT'S NEW?</article-title><trans-title-group xml:lang="ru"><trans-title>АНТИТРОМБОТИЧЕСКАЯ ТЕРАПИЯ ПАЦИЕНТОВ С КЛАПАННОЙ БОЛЕЗНЬЮ СЕРДЦА: ЧТО НОВОГО?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shostak</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Шостак</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Faculty Therapy named after Acad. A.I. Nesterov.</p><p> 1 Ostrovityanova St., Moscow 117997.</p></bio><bio xml:lang="ru"><p>Кафедра факультетской терапии им. акад. А.И. Нестерова.</p><p> 117997 Москва, ул. Островитянова, 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Klimenko</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Клименко</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Faculty Therapy named after Acad. A.I. Nesterov.</p><p> 1 Ostrovityanova St., Moscow 117997.</p></bio><bio xml:lang="ru"><p>Кафедра факультетской терапии им. акад. А.И. Нестерова.</p><p> 117997 Москва, ул. Островитянова, 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Andriyashkina</surname><given-names>D. Yu.</given-names></name><name xml:lang="ru"><surname>Андрияшкина</surname><given-names>Д. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Faculty Therapy named after Acad. A.I. Nesterov.</p><p> 1 Ostrovityanova St., Moscow 117997.</p></bio><bio xml:lang="ru"><p>Кафедра факультетской терапии им. акад. А.И. Нестерова.</p><p> 117997 Москва, ул. Островитянова, 1.</p></bio><email>andryashkina.darya@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Demidova</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Демидова</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Faculty Therapy named after Acad. A.I. Nesterov.</p><p> 1 Ostrovityanova St., Moscow 117997.</p></bio><bio xml:lang="ru"><p>Кафедра факультетской терапии им. акад. А.И. Нестерова.</p><p> 117997 Москва, ул. Островитянова, 1.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.I. Pirogov Russian National Research Medical University,  Ministry of Health of Russia.</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России.</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2017</year></pub-date><volume>11</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>10</fpage><lpage>15</lpage><history><date date-type="received" iso-8601-date="2017-12-18"><day>18</day><month>12</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-12-18"><day>18</day><month>12</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Shostak N.A., Klimenko A.A., Andriyashkina D.Y., Demidova N.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Шостак Н.А., Клименко А.А., Андрияшкина Д.Ю., Демидова Н.А.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Shostak N.A., Klimenko A.A., Andriyashkina D.Y., Demidova N.A.</copyright-holder><copyright-holder xml:lang="ru">Шостак Н.А., Клименко А.А., Андрияшкина Д.Ю., Демидова Н.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/306">https://klinitsist.abvpress.ru/Klin/article/view/306</self-uri><abstract xml:lang="en"><p>The article presents an overview of modern data and an analysis of the recommendations of the European Society of Cardiology and the European Association for Cardio-Thoracic Surgery published in 2017 regarding the use of antithrombotic therapy in patients with valvular heart disease. The results of studies devoted to the use of new oral anticoagulants in patients with valvular heart disease are demonstrated.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлен обзор современных данных и анализ опубликованных в 2017 г. рекомендаций Европейского общества кардиологов и Европейской ассоциации кардиоторакальной хирургии относительно применения антитромботической терапии у пациентов с клапанной болезнью сердца. Продемонстрированы результаты исследований, посвященных применению новых оральных антикоагулянтов при клапанной болезни сердца.</p></trans-abstract><kwd-group xml:lang="en"><kwd>heart defects</kwd><kwd>valvular heart disease</kwd><kwd>valvular pathology</kwd><kwd>atrial fibrillation</kwd><kwd>mitral stenosis</kwd><kwd>mitral regurgitation</kwd><kwd>aortic regurgitation</kwd><kwd>aortic stenosis</kwd><kwd>warfarin</kwd><kwd>vitamin K antagonists</kwd><kwd>new oral anticoagulants</kwd><kwd>rivaroxaban</kwd><kwd>apixaban</kwd><kwd>dabigatran</kwd><kwd>edoxaban</kwd><kwd>ablation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>пороки сердца</kwd><kwd>клапанная болезнь сердца</kwd><kwd>клапанная патология</kwd><kwd>фибрилляция предсердий</kwd><kwd>митральный стеноз</kwd><kwd>митральная регургитация</kwd><kwd>аортальная регургитация</kwd><kwd>аортальный стеноз</kwd><kwd>варфарин</kwd><kwd>антагонисты витамина К</kwd><kwd>новые оральные антикоагулянты</kwd><kwd>ривароксабан</kwd><kwd>апиксабан</kwd><kwd>дабигатран</kwd><kwd>эдоксабан</kwd><kwd>аблация</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Рекомендации РКО, ВНОА, АССХ. 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