The ClinicianThe ClinicianКлиницист1818-83382412-8775Publishing House ABV Press2610.17650/1818-8338-2013-7-2-ORIGINAL INVESTIGATIONSОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE DECOMPENSATED CHRONIC HEART FAILUREОстрое повреждение почек у больных с острой декомпенсацией хронической сердечной недостаточностиMenzorovM. V.МензоровМ. В.
Russian Federation
menzorov.m.v@yandex.ruShutovA. M.ШутовА. М.
Russian Federation
MakeevaE. R.МакееваЕ. Р.
Russian Federation
StrakhovA. A.СтраховА. А.
Russian Federation
Ulyanovsk State UniversityФГБОУ ВПО «Ульяновский государственный университет»Central City Clinical Hospital, UlyanovskГУЗ «Центральная городская клиническая больница г. Ульяновска»150420137229331407201414072014Copyright ©; 2013, Menzorov M.V., Shutov A.M., Makeeva E.R., Strakhov A.A.Copyright ©; 2013, Мензоров М.В., Шутов А.М., Макеева Е.Р., Страхов А.А.2013Menzorov M.V., Shutov A.M., Makeeva E.R., Strakhov A.A.Мензоров М.В., Шутов А.М., Макеева Е.Р., Страхов А.А.https://creativecommons.org/licenses/by/4.0https://klinitsist.abvpress.ru/Klin/article/view/26

Objective: to estimate the frequency and magnitude of acute kidney injury (AKI) in patients with acute decompensated chronic heart failure(ADCHF) and to clarify the relationship of AKI to mortality.

Subjects and methods. One hundred and four patients (58 men and 46 women; mean age 65.3 ± 10.68 years) with ADCHF were examined.AKI was diagnosed and classified by the KDIGO criteria.

Results. In terms of creatinine, AKI was diagnosed in 74 (71 %) patients (Stage I in 51 (49 %), Stage II in 20 (19 %), and Stage III in 3 (3 %)patients. Five (5 %) patients died during hospitalization. All the dead patients had AKI. Multivariate regression analysis demonstrated that regardless of gender, age, chronic heart failure stage, the in-hospital mortality was associated with the level of creatinine (R = 0.29; β = 0.20;p = 0.046). At the same time, in the patients with AKI Stages II-III the probability of in-hospital mortality was higher than that in the other patients (relative risk, 23.4; 95 % confidence interval 2.9–187.0; p = 0.003).

Conclusion. More than half of the patients with ADCHF have AKI according to the KRIGO criteria. The in-hospital mortality is much higheramongst the patients with AKI Stages II-III.

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