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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">162</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2014-2-33-38</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL INVESTIGATIONS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">PECULIARITIES OF INTERCELLULAR SUBSTANCE METABOLISM OF PATIENTS WITH OSTEOARTHRITIS AND CONNECTIVE TISSUE DYSPLASIA</article-title><trans-title-group xml:lang="ru"><trans-title>ОСОБЕННОСТИ МЕТАБОЛИЗМА МЕЖКЛЕТОЧНОГО ВЕЩЕСТВА У ПАЦИЕНТОК С ОСТЕОАРТРИТОМ И ДИСПЛАЗИЕЙ СОЕДИНИТЕЛЬНОЙ ТКАНИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tyurin</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Тюрин</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>anton.bgmu@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Davletshin</surname><given-names>R. A.</given-names></name><name xml:lang="ru"><surname>Давлетшин</surname><given-names>Р. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Farkhutdinov</surname><given-names>R. R.</given-names></name><name xml:lang="ru"><surname>Фархутдинов</surname><given-names>Р. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zaripova</surname><given-names>R. M.</given-names></name><name xml:lang="ru"><surname>Зарипова</surname><given-names>Р. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Davletshin</surname><given-names>T. R.</given-names></name><name xml:lang="ru"><surname>Давлетшин</surname><given-names>Т. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Bashkir State Medical University, Ministry of Health of Russia, 3 Lenin St., Ufa, 450000, Russia</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Башкирский государственный медицинский университет» Минздрава России, Россия, 450000, Уфа, ул. Ленина, 3</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2014</year></pub-date><volume>8</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>33</fpage><lpage>38</lpage><history><date date-type="received" iso-8601-date="2015-01-30"><day>30</day><month>01</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-01-30"><day>30</day><month>01</month><year>2015</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Tyurin A.V., Davletshin R.A., Farkhutdinov R.R., Zaripova R.M., Davletshin T.R.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Тюрин А.В., Давлетшин Р.А., Фархутдинов Р.Р., Зарипова Р.М., Давлетшин Т.Р.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Tyurin A.V., Davletshin R.A., Farkhutdinov R.R., Zaripova R.M., Davletshin T.R.</copyright-holder><copyright-holder xml:lang="ru">Тюрин А.В., Давлетшин Р.А., Фархутдинов Р.Р., Зарипова Р.М., Давлетшин Т.Р.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/162">https://klinitsist.abvpress.ru/Klin/article/view/162</self-uri><abstract xml:lang="en"><p/></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>osteoarthritis</kwd><kwd>osteoarthrosis</kwd><kwd>connective tissue dysplasia</kwd><kwd>phenotypic characteristics of dysplasia</kwd><kwd>glycosaminoglycans</kwd><kwd>cartilage oligomeric matrix protein</kwd><kwd>intercellular substance</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>остеоартрит</kwd><kwd>остеоартроз</kwd><kwd>дисплазия соединительной ткани</kwd><kwd>фенотипические признаки дисплазии</kwd><kwd>гликоза- миногликаны</kwd><kwd>олигомерный хрящевой матриксный протеин</kwd><kwd>межклеточное вещество</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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