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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">158</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2014-2-7-16</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">RENAL DAMAGE WITH MALIGNANT NEOPLASMS</article-title><trans-title-group xml:lang="ru"><trans-title>ПОРАЖЕНИЕ ПОЧЕК ПРИ ЗЛОКАЧЕСТВЕННЫХ ОБРАЗОВАНИЯХ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kolina</surname><given-names>I. B.</given-names></name><name xml:lang="ru"><surname>Колина</surname><given-names>И. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>ikolina@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bobkova</surname><given-names>I. N.</given-names></name><name xml:lang="ru"><surname>Бобкова</surname><given-names>И. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, 2 Bolshaya Pirogovskaya St., bldg. 4, Moscow, 119991, Russia</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Минздрава России, Россия, 119991, Москва, ул. Большая Пироговская, 2, стр. 4</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2014</year></pub-date><volume>8</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>7</fpage><lpage>16</lpage><history><date date-type="received" iso-8601-date="2015-01-30"><day>30</day><month>01</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-01-30"><day>30</day><month>01</month><year>2015</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Kolina I.B., Bobkova I.N.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Колина И.Б., Бобкова И.Н.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Kolina I.B., Bobkova I.N.</copyright-holder><copyright-holder xml:lang="ru">Колина И.Б., Бобкова И.Н.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/158">https://klinitsist.abvpress.ru/Klin/article/view/158</self-uri><abstract xml:lang="en"><p>The relationship between renal damage and malignant neoplasms is one of the most actual problems of the medicine of internal diseases. Very often, exactly availability of renal damage determines the forecast of cancer patients. The range of renal pathologies associated with tumors is unusually wide: from the mechanical effect of the tumor or metastases on the kidneys and/or the urinary tract and paraneoplastic manifestations in the form of nephritis or amyloidosis to nephropathies induced with drugs or tumor lysis, etc. Thrombotic complications that develop as a result of exposure to tumor effects, side effects of certain drugs or irradiation also play an important role in the development of the kidney damage. The most frequent variants of renal damage observed in the practice of medical internists (therapists, urologists, surgeons, etc.), as well as methods of diagnosis and treatment approaches are described in the article. Timely and successful prevention and treatment of tumor-associated nephropathies give hope for retaining renal functions, therefore, a higher life standard after completion of anti-tumor therapy. Even a shortterm episode of acute renal damage suffered by a cancer patient must be accompanied with relevant examination and treatment. In the caseof transformation of acute renal damage into the chronic kidney disease, such patients need systematic and weighted renoprotective therapy and correct dosing of nephrotoxic drugs.</p></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>tumor-associated nephropathies</kwd><kwd>renal damage with tumors</kwd><kwd>acute renal failure</kwd><kwd>nephrotoxicity of chemotherapy</kwd><kwd>paraneoplastic nephropathies</kwd><kwd>acute renal damage with tumors</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>опухоль-ассоциированные нефропатии</kwd><kwd>поражение почек при опухолях</kwd><kwd>острая почечная недостаточность</kwd><kwd>нефротоксическое действие химиопрепаратов</kwd><kwd>паранеопластические нефропатии</kwd><kwd>острое почечное повреждение при опухолях</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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