The ClinicianThe ClinicianКлиницист1818-83382412-8775Publishing House ABV Press15210.17650/1818-8338-2014-1-77-81CASE REPORTОПИСАНИЕ СЛУЧАЯUSE OF EXTENDED-RELEASE PRAMIPEXOLE IN EARLY-STAGE PARKINSON’S DISEASE: DESCRIPTION OF A CLINICAL CASEПРИМЕНЕНИЕ ПРОЛОНГИРОВАННОГО ПРАМИПЕКСОЛА НА РАННЕЙ СТАДИИ БОЛЕЗНИ ПАРКИНСОНА: ОПИСАНИЕ КЛИНИЧЕСКОГО СЛУЧАЯFedorovaN. V.ФедороваН. В.
Russian Federation
natalia.fedorova@list.ruGubanovaYe. N.ГубановаЕ. Н.
Russian Federation
Center of Extrapyramidal Diseases, Department of Neurology, Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia, MoscowЦентр экстрапирамидных заболеваний нервной системы, кафедра неврологии ГБОУ ДПО «Российская медицинская академия последипломного образования» Минздрава России, Москва150120148177812311201423112014Copyright ©; 2014, Fedorova N.V., Gubanova Y.N.Copyright ©; 2014, Федорова Н.В., Губанова Е.Н.2014Fedorova N.V., Gubanova Y.N.Федорова Н.В., Губанова Е.Н.https://creativecommons.org/licenses/by/4.0https://klinitsist.abvpress.ru/Klin/article/view/152

The paper considers a clinical case of early-stage mixed Parkinson’s disease (PD) with significant affective disorders and restless legs syndrome. Once-daily extended-release pramipexole 3 mg significantly improved a patient’s status and led to regression of movement and affective disorders. The paper gives data on the efficacy of dopamine receptor agonists in treating PD and the benefits of their extended-release formulations.

В статье рассматривается клинический случай ранней стадии смешанной формы болезни Паркинсона (БП) с выраженными аффективными нарушениями и синдромом беспокойных ног. Назначение 3 мг пролонгированной формы прамипексола однократно в сутки значительно улучшило состояние больной, привело к регрессу двигательных симптомов и аффективных нарушений. Приводятся данные об эффективности агонистов дофаминовых рецепторов в лечении БП и преимуществах пролонгированныхформ препаратов.

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