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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">The Clinician</journal-id><journal-title-group><journal-title xml:lang="en">The Clinician</journal-title><trans-title-group xml:lang="ru"><trans-title>Клиницист</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1818-8338</issn><issn publication-format="electronic">2412-8775</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">131</article-id><article-id pub-id-type="doi">10.17650/1818-8338-2011-1-14-17</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION: NEW ASPECTS OF THE DEVELOPMENT AND PROGRESSION OF THE DISEASE</article-title><trans-title-group xml:lang="ru"><trans-title>ХРОНИЧЕСКАЯ ПОСТЭМБОЛИЧЕСКАЯ ЛЕГОЧНАЯ ГИПЕРТЕНЗИЯ: НОВЫЕ АСПЕКТЫ ФОРМИРОВАНИЯ И ПРОГРЕССИРОВАНИЯ ЗАБОЛЕВАНИЯ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Klimenko</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Клименко</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Acad. A.I. Nesterov Department of Faculty Therapy</p></bio><bio xml:lang="ru"><p>Кафедра факультетской терапии им. акад. А.И. Нестерова</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shostak</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Шостак</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Acad. A.I. Nesterov Department of Faculty Therapy</p></bio><bio xml:lang="ru"><p>Кафедра факультетской терапии им. акад. А.И. Нестерова</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Demidova</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Демидова</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Acad. A.I. Nesterov Department of Faculty Therapy</p></bio><bio xml:lang="ru"><p>Кафедра факультетской терапии им. акад. А.И. Нестерова</p></bio><email>ntverdova@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Novikov</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Новиков</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Acad. A.I. Nesterov Department of Faculty Therapy</p></bio><bio xml:lang="ru"><p>Кафедра факультетской терапии им. акад. А.И. Нестерова</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian State Medical University, Russian Agency for Health Care</institution></aff><aff><institution xml:lang="ru">ГОУ ВПО РГМУ Росздрава</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-01-15" publication-format="electronic"><day>15</day><month>01</month><year>2011</year></pub-date><volume>5</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>14</fpage><lpage>17</lpage><history><date date-type="received" iso-8601-date="2014-07-18"><day>18</day><month>07</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-07-18"><day>18</day><month>07</month><year>2014</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2011, Klimenko A.A., Shostak N.A., Demidova N.A., Novikov I.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2011, Клименко А.А., Шостак Н.А., Демидова Н.А., Новиков И.В.</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="en">Klimenko A.A., Shostak N.A., Demidova N.A., Novikov I.V.</copyright-holder><copyright-holder xml:lang="ru">Клименко А.А., Шостак Н.А., Демидова Н.А., Новиков И.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://klinitsist.abvpress.ru/Klin/article/view/131">https://klinitsist.abvpress.ru/Klin/article/view/131</self-uri><abstract xml:lang="en"><p>The review presents data on the incidence of chronic thromboembolic pulmonary hypertension after pulmonary thromboembolism and describescongenital and acquired coagulation abnormalities in patients with venous thromboembolism. It considers the potential factors of development of chronic thromboembolic pulmonary hypertension and some medical conditions and diseases, which favors the development of pulmonary hypertension after prior pulmonary thromboembolism.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре представлены данные о частоте развития хронической постэмболической легочной гипертензии после тромбоэмболии легочной артерии, описаны врожденные и приобретенные аномалии коагуляции у пациентов с венозным тромбоэмболизмом. Рассмотрены потенциальные факторы формирования хронической постэмболической легочной гипертензии, а также некоторыемедицинские состояния и заболевания, способствующие развитию легочной гипертензии после перенесенной тромбоэмболии легочной артерии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>pulmonary hypertension</kwd><kwd>chronic thromboembolic pulmonary hypertension</kwd><kwd>pulmonary thromboembolism</kwd><kwd>congenital thrombophilia</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>легочная гипертензия</kwd><kwd>хроническая постэмболическая легочная гипертензия</kwd><kwd>тромбоэмболия легочной артерии</kwd><kwd>врожденная тромбофилия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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