The ClinicianThe ClinicianКлиницист1818-83382412-8775Publishing House ABV Press12510.17650/1818-8338-2011-2-72-79PHARMACOTHERAPYФАРМАКОТЕРАПИЯANTIPLATELET THERAPY IN PATIENTS WITH HIGH RISK OF THROMBOTIC EVENTS: THE PROBLEM OF EFFICIENCY, SAFETY AND COMPLIANCEАНТИАГРЕГАНТНАЯ ТЕРАПИЯ У БОЛЬНЫХ С ВЫСОКИМ РИСКОМ РАЗВИТИЯ ТРОМБОТИЧЕСКИХ ОСЛОЖНЕНИЙ: ПРОБЛЕМА ЭФФЕКТИВНОСТИ, БЕЗОПАСНОСТИ И ПРИВЕРЖЕННОСТИMartsevichS. Yu.МарцевичС. Ю.
Russian Federation

Кафедра доказательной медицины

smartsevich@gnicpm.ruKutishenkoN. P.КутишенкоН. П.
Russian Federation
GinzburgM. L.ГинзбургМ. Л.
Russian Federation
MalyshevaA. M.МалышеваА. М.
Russian Federation
PolyanskayaYu. N.ПолянскаяЮ. Н.
Russian Federation
State Research Center for Preventive Medicine, Ministry of Health and Social Development of Russia I.M. Sechenov First Moscow State Medical UniversityГосударственный научно-исследовательский центр профилактической медицины Минздравсоцразвития России 1-ый МГМУ им. И.М. СеченоваState Research Center for Preventive Medicine, Ministry of Health and Social Development of RussiaГосударственный научно-исследовательский центр профилактической медицины Минздравсоцразвития РоссииLyubertsy District Hospital № 2, Moscow RegionЛюберецкая районная больница № 2, Московская область150420115272791707201417072014Copyright ©; 2011, Martsevich S.Y., Kutishenko N.P., Ginzburg M.L., Malysheva A.M., Polyanskaya Y.N.Copyright ©; 2011, Марцевич С.Ю., Кутишенко Н.П., Гинзбург М.Л., Малышева А.М., Полянская Ю.Н.2011Martsevich S.Y., Kutishenko N.P., Ginzburg M.L., Malysheva A.M., Polyanskaya Y.N.Марцевич С.Ю., Кутишенко Н.П., Гинзбург М.Л., Малышева А.М., Полянская Ю.Н.https://creativecommons.org/licenses/by/4.0https://klinitsist.abvpress.ru/Klin/article/view/125

Evidence based medicine data on ability of antiplatelet, including dual antiplatelet, therapy to improve the life expectancy of patients with high risk of thrombotic complications, especially patients with acute myocardial infarction is presented in brief. The problem of choosing a drug and resistance was overcoming. Modern clinical guidelines on safe antiplatelet therapy are presented.

Приведены краткие данные доказательной медицины о способности антиагрегантов, в том числе назначаемых совместно (двойная антиагрегантная терапия), улучшать прогноз жизни больных с высоким риском развития тромботических осложнений, в первую очередь пациентов, перенесших острый инфаркт миокарда. Рассмотрены проблемы выбора препарата и преодоления резистентности к нему. Представлены современные рекомендации по обеспечению безопасности терапии антиагрегантами.

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