Email this article Comprehensive conservative treatment as a possible alternative to surgery in difficult orthopedic situations
- Authors: Samoday V.G.1, Varfolomeev D.I.1, Kuznetsova V.P.1, Rylkov M.I.1
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Affiliations:
- N. N. Burdenko Voronezh State Medical University, Ministry of Health of Russia
- Issue: Vol 16, No 2 (2022)
- Pages: 58-63
- Section: PHARMACOTHERAPY
- Published: 11.10.2022
- URL: https://klinitsist.abvpress.ru/Klin/article/view/498
- DOI: https://doi.org/10.17650/1818-8338-2022-16-2-K662
- ID: 498
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Abstract
Osteoarthritis, both idiopathic and post-traumatic, is currently the most significant problem in orthopedics. It is particularly difficult to treat patient with comorbidities, when it is necessary to decide on surgery for a late-stage joint disease. An operation is associated with a great risk in such patients. Even if the patient does not have serious somatic disorders, the main task of doctors (and this is a multidisciplinary problem) is to prolong joint functioning and maintain the patient’s quality of life.
In this article, we report difficult cases, when a complex of non-pharmacological (therapeutic exercise, physiotherapy, orthobiology – PRP therapy) and pharmacological (nonsteroidal anti-inflammatory drugs, chondroprotectors, vitamins, calcium, tissue repair stimulants) treatments ensured a good effect, thereby maintaining the joint function and adequate quality of life without surgery. We also found that the use of Ambene® Bio (a chondroprotector) increased treatment efficacy.
About the authors
V. G. Samoday
N. N. Burdenko Voronezh State Medical University, Ministry of Health of Russia
Author for correspondence.
Email: V_Samoday@mail.ru
ORCID iD: 0000-0003-1414-0832
Valeriy Grigoryevich Samoday
10 Studencheskaya St., Voronezh, 394036
Russian FederationD. I. Varfolomeev
N. N. Burdenko Voronezh State Medical University, Ministry of Health of Russia
ORCID iD: 0000-0002-2133-6510
10 Studencheskaya St., Voronezh, 394036
Russian FederationV. P. Kuznetsova
N. N. Burdenko Voronezh State Medical University, Ministry of Health of Russia
ORCID iD: 0000-0002-4642-9115
10 Studencheskaya St., Voronezh, 394036
Russian FederationM. I. Rylkov
N. N. Burdenko Voronezh State Medical University, Ministry of Health of Russia
ORCID iD: 0000-0003-1543-7064
10 Studencheskaya St., Voronezh, 394036
Russian FederationReferences
- Glyn-Jones S., Palmer A.J., Agricola R. et al. Osteoarthritis. Lancet 2015;386(9991):376–87. doi: 10.1016/S0140-6736(14)60802-3
- Shirokova I., Prozherina J. Osteoarthritis in the 21st century. Challenges and solutions. Remedium = Remedium 2017(10):33–6. (In Russ.) doi: 10.21518/1561-5936-2017-10-33-36
- Luchikhina L.V., Mendel O.I., Mendel V. et al. Osteoarthritis and age. Role of aging in the etiology and pathogenesis of the disease. Sovremennaya revmatologiya = Modern Rheumatology Journal 2017;11(1): 4–11. (In Russ.) doi: 10.14412/1996-7012-2017-1-4-11
- Osteoarthritis. Clinical guidelines of the Russian Federation 2013-2017 (Russia), 2013 (In Russ.).
- Swain S., Sarmanova A., Coupland C. et al. Comorbidities in оsteoarthritis: a systematic review and metaanalysis of observational studies. Arthritis Care Res (Hoboken) 2020;72(7):991–1000. doi: 10.1002/acr.24008
- Shavlovskaya O.A., Zolotovskaya I.A., Prokofyeva Yu.S. Antiinflammatory and anti-aging effects of chondroitin sulfate. Nevrologiya, neyropsihiatriya, psihosomatika = Neurology, Neuropsychiatry, Psychosomatics 2020;12(5):111–6. (In Russ.) doi: 10.14412/2074-2711-2020-5-111-116
- Menshikova I.V., Sorotskaya V.I. Treatment of osteoarthritis of large and small joints using an injectable complex action chondroprotector. Lechaschi vrach = Attending physician 2021;4(24):66–71. (In Russ.) doi: 10.51793/OS.2021.14.17.012
- Karateev A.E., Nasonov E.L., Ivashkin V.T. et al. Rational use of nonsteroidal anti-inflammatory drugs. Clinical guidelines. Nauchno-prakticheskaya revmatologiya = Rheumatology Science and Practice. 2018;56:1–29. (In Russ.) doi: 10.14412/1995-4484-2018-1-29
- Clinical guidelines of the Russian Federation 2021 (Russia) (In Russ.).
- Нормативная документация: Фармакопейная статья на субстанцию-жидкость «биоактивный экстракт из мелкой морской рыбы». https://zdravmedinform.ru. Regulatory document “Pharmacopoeial monograph on “bioactive extract from small sea fish”. https://zdravmedinform.ru (In Russ.).
- Danilov A.B., Zotkin Ye.G. Medical duo: osteoarthritis and osteochondrosis – the consensus of a neurologist and a rheumatologist. Effektivnaya farmakoterapiya = Effective pharmacotherapy 2022;18(5):44–8. (In Russ.).
- Feklistov A.Yu., Vorobyova L.D., Alekseeva O.G. et al. Results of a non-interventional study “Colibri” to evaluate the efficacy and safety of Ambene® Bio in patients with primary and secondary osteoarthritis of various localization. RMZH. Medicinskoe obozrenie = Russian Medical Journal 2022;6(3):126–32. (In Russ.) doi: 10.32364/2587-6821-2022-6-3-126-132
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