CASE OF CENTRAL NEUROCYTOMA

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Abstract

The aim of study was to describe a clinical case of central neurocytoma formation and course.

Materials and methods. Patient C., 33 years old, admitted to the neurosurgical department of Regional Clinical Hospital with complaints of headache and sleep disturbance that troubled her for 2 months. No chronic diseases were detected. During the stay in the hospital, the patient was carried out a number of examinations: assessment of laboratory parameters in dynamics, magnetic resonance imaging of the brain, examination by specialists (neurologist, neuroophthalmologist).

Results. Magnetic resonance imaging of the brain revealed a solid volume cystic formation of the left frontal lobe. Bone plastic trepanation and microsurgical removal of the intracerebral cystic tumor in the left frontal area were performed. Revealed neuroradiological and histological characteristics allowed differentiation of neurocytoma from other histological variants. According to magnetic resonance imaging no tumor growth was observed 5 months after surgery. A course of radiation therapy was conducted.

Conclusion. This clinical case presented the peculiarities of the course, diagnosis, surgery and immunohistochemical analysis of patient with central neurocytoma.

About the authors

I. S. Kurepina

Ryazan State Medical University named after academician I.P. Pavlov, Ministry of Health of Russia

Author for correspondence.
Email: innakurepina90@mail.ru

9 Vysokovoltnaya St., Ryazan 390026

Russian Federation

R. A. Zorin

Ryazan State Medical University named after academician I.P. Pavlov, Ministry of Health of Russia

ORCID iD: 0000-0003-4310-8786

9 Vysokovoltnaya St., Ryazan 390026

Russian Federation

A. I. Prokudin

Regional Clinical Hospital

ORCID iD: 0000-0001-7332-3263

3a Internatsionalnaya St., Ryazan 390039

Russian Federation

References

  1. Lee S.J., Bui T.T., Chen C.H. et al. Central neurocytoma: a review of clinical management and histopathologic features. Brain Tumor Res Treat 2016;4(2):49–57. doi: 10.14791/btrt.2016.4.2.49.
  2. Hassoun J., Gambarelli D., Grisoli F. et al. Central neurocytoma. An electron microscopic study of two cases. Acta Neuropathol 1982;56(2):151–6. doi: 10.1007/bf00690587.
  3. Ishiuchi S., Tamura M. Central neurocytoma: an immuno histochemical, ultrastructural and cell culture study. Acta Neuropathol 1997;94(4):425–35. doi: 10.1007/s004010050729.
  4. Pronin I.N., Konovalov A.N., Maryashev S.A. et al. Neuroradiological characteristics of cerebral neurocytomas. Medicinskaya nejrovizualizaciya = Medical Brain Imaging 2002;(1):6–16. (In Russ.)
  5. Louis D.N., Ohgaki H., Wiestler W.K. et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007;114(2):97–109. doi: 10.1007/s00401-007-0278-6.
  6. Louis D.N., Perry A., Reifenberger G. et al. The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 2016;131(6):803–20. doi: 10.1007/s00401-016-1545-1.
  7. Galanov V.A., Maryashev S.A., Korshunov A.G., Pronin I.N. Central neurocytomas of brain. Voprosy nejrohirurgii imeni N.N. Burdenko = Problems of Neurosurgery named after N.N. Burdenko 2001;(4):36–9. (In Russ.)
  8. Matsunaga S., Shuto T., Suenaga J. et al. Gamma knife radiosurgery for central neurocytomas. Neurol Med Chir (Tokio) 2010;50(2):107–12; discussion 112–3. doi: 10.2176/nmc.50.107.
  9. Yen P.S., Wong M.C., Wai Y.Y. et al. MR imaging of intraventricular neurocytoma. Chin J Radiol 2000;25:197–201.
  10. Nazarova A.A., Gradykina Yu.S. Use of catalase activity parameters for differential diagnosis of malignant and benign neoplasms of brain tumors. Nauka molodykh (Eruditio Juvenium) = Science of Youth (Eruditio Juvenium) 2017;5(2):192–8. (In Russ.)
  11. Rytikova N.S., Smirnova M.A., Ugol’nikova N.V. Markers of nervous system disorders. In: Katalog BioHimMak = Catalog BioChimMak, 2007. P. 72–84. (In Russ.)
  12. Shpon’ka I. S., Shinkarenko T.V. Diagnostic significance of the structural characteristics of microvascular brain glial tumors. Rossijskij mediko-biologicheskij vestnik imeni akademika I.P. Pavlova = I.P. Pavlov Russian Medical Biological Herald 2017;25(3):350–61. (In Russ.)
  13. Tonoyan A.S., Pronin I.N., Pitskhelauri D.I. et al. Correlation of diffusion-kurtosis MRI with proliferative activity of brain gliomas. Voprosy nejrohirurgii imeni N.N. Burdenko = Problems of Neurosurgery named after N.N. Burdenko 2015;79(6):5–14 (In Russ.)
  14. Sharma S., Sarkar C., Gaikwad S. et al. Primary neurocytoma of the spinal cord: a case report and review of literature. J Neurooncol 2005;74(1):47–52. doi: 10.1007/s11060-004-3348-9.
  15. Takao H., Nakagawa K., Ohtomo K. Central neurocytoma with craniospinal dissemination. J Neurooncol 2003;61(3):255–9.
  16. Brandes A.A., Amista P., Gardiman M. et al. Chemotherapy in patients with recurrent and progressive central neurocytoma. Cancer 2000;88:169–74.
  17. Elek G., Slowik F., Eross L. et al. Central neurocytoma with malignant course: neuronal and glial differentiation and craniospinal dissemination. Pathol Oncol Res 1999;5(2):155–9.
  18. Eng D.Y., De Monte F., Ginsberg L. et al. Craniospinal dissemination of central neurocytoma. Report of two cases. J Neurosurg 1997;86(3):547–52.

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