Email this article 24-HOUR ARTERIAL STIFFNESS PROFILE IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND CHRONIC HEART FAILURE
- Authors: Borodkin A.V.1,2, Karoli N.A.1,2, Rebrov A.P.1,2
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Affiliations:
- V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia
- 112 Bolshaya Kazachya St., Saratov, 410012, Russia
- Issue: Vol 9, No 3 (2015)
- Pages: 40-45
- Section: ORIGINAL INVESTIGATIONS
- Published: 12.10.2015
- URL: https://klinitsist.abvpress.ru/Klin/article/view/209
- DOI: https://doi.org/10.17650/1818-8338-2015-9-3-40-45
- ID: 209
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Abstract
Objective: to study the specific features of arterial stiffness (AS) in patients with chronic obstructive pulmonary disease (COPD) and chronic heart failure (CHF) as evidenced by 24hour monitoring.
Subjects and methods. A total of 111 patients with COPD, including 76 with signs of CHF, were examined. The patients with COPD and CHF were divided into 2 groups according to the presence or absence of prior myocardial infarction (MI). A BPLab МнСДП2 apparatus was used to study 24hour AS monitoring readings.
Results. The patients with COPD and CHF were noted to have higher values of AS index (ASI) (during a day, daytime) and pulse wave propa gation velocity (during a day, daytime, nighttime) than those with COPD without CHF. There was an association between ASI and major car diovascular risk factors (hypertension, age, body mass index). The patients with COPD, CHF, and prior MI, unlike those without the latter, were found to have an increased augmentation index throughout the followup (during both daytime and nighttime). In the patients with CHF without prior MI, the diurnal ASI was considerably greater than that in both the COPD patients without CHF and those with CHF and prior MI.
Conclusion. Increased vascular wall stiffness was detected in the patients with COPD and CHF. By taking into account pronounced AS changes not only during daytime and nighttime hours, it is reasonable to perform 24hour AS monitoring in patients with comorbidities in order to obtain more objective results.
About the authors
A. V. Borodkin
V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia; 112 Bolshaya Kazachya St., Saratov, 410012, Russia
Author for correspondence.
Russian Federation
N. A. Karoli
V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia; 112 Bolshaya Kazachya St., Saratov, 410012, Russia
Email: andreyrebrov@yandex.ru
Russian Federation
A. P. Rebrov
V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia; 112 Bolshaya Kazachya St., Saratov, 410012, RussiaRussian Federation
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