METABOLIC DISTURBANCES IN THE FUTURE DEVELOPMENT AND PROGRESSION OF ARTERIAL HYPERTENSION IN YOUNG MEN

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Abstract

Objective: to reveal carbohydrate and lipid metabolic disturbances and their possible importance in examined young men with early arterial hypertension (AH).
Subjects and methods. A total of 130 men aged 40.3 ± 4.3 years were examined. There were 3 patient groups: stage I hypertensive disease with a history of AH (n = 61); primarily diagnosed hypertensive disease without evidence of long-term AH (n = 39); a control group noncardiovascular diseases (n = 30).
Results. The patients with long-term AH were more commonly found to have a compromised history of cardiovascular diseases and type 2 diabetes mellitus, signs of insulin resistance and subclinical atherosclerosis than those with the primarily diagnosed disease and the control group.
Conclusion. Carbohydrate and lipid metabolic disturbances are latent in young men with long-term AH. Both 2and 1-hour oral glucose tolerance tests are recommended for the early diagnosis of glycemic disorders in the above patient cohort. 

About the authors

A. V. Gordienko

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, Russia

Author for correspondence.
Russian Federation

M. A. Mirokhina

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, Russia

Russian Federation

V. T. Dydyshko

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, Russia

Russian Federation

D. Yu. Serdyukov

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, Russia

Email: serdukovdu@yandex.ru
Russian Federation

A. S. Fedorova

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, Russia

Russian Federation

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