CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME

A. V. Markin; Маркин А. В.; T. I. Martynenko; Мартыненко Т. И.; G. I. Kostyuchenko; Костюченко Г. И.; I. Ya. Tseimakh; Цеймах И. Я.; Ya. N. Shoikhet; Шойхет Я. Н.

doi:10.17650/1818-8338-2014-1-15-21

CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME

Authors: Markin A.V.¹, Martynenko T.I.², Kostyuchenko G.I.³, Tseimakh I.Y.⁴, Shoikhet Y.N.⁴
Affiliations:
1. Altai State Medical University, Ministry of Health of Russia, Barnaul City Hospital Five, Barnaul
2. City Hospital Five, Barnaul
3. Regional Clinical Hospital, Barnaul
4. Altai State Medical University, Ministry of Health of Russia, Barnaul
Issue: Vol 8, No 1 (2014)
Pages: 15-21
Section: REVIEW
Published: 23.11.2014
URL: https://klinitsist.abvpress.ru/Klin/article/view/142
DOI: https://doi.org/10.17650/1818-8338-2014-1-15-21
ID: 142

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Abstract

The paper analyzes the cause-and-effect relations of obstructive sleep apnea syndrome (OSAS) and cardiovascular diseases (CVD). In OSAS,
there is activation of the sympathetic nervous system and proinflammatory and procoagulant systems, endothelial dysfunction, and accelerated atherosclerosis in response to intermittent hypoxia and sleep fragmentation, which leads to increased risk for CVD. Continuous positive airway pressure therapy reduces the risk of death in patients with OSAS