BACK PAIN ASSOCIATED WITH INTERVERTEBRAL DISK DEGENERATION: MORPHOLOGICAL, GENETIC AND CLINICO-INSTRUMENTAL ASPECTS

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Abstract

Degenerative spine disease is one of the causes of back pain. Clinical types of pain and severity of inflammatory changes in the vertebral bodies depend on the activity of pro-inflammatory cytokines. Rate of development and progression of degenerative changes in the spine structures is genetically determined. Therapy of pain syndrome associated with a degenerative disc disease may include use of methods to restore damaged intervertebral disc structures, and also use of different combinations of anti-inflammatory and analgesics therapy.

About the authors

N. A. Shostak

Russian State Medical University, Ministry of Health and Social Development of Russia

Acad. A.I. Nesterov’s Therapy Department Russian Federation

N. G. Pravdyuk

Russian State Medical University, Ministry of Health and Social Development of Russia

Author for correspondence.
Email: pravda547@yandex.ru
Acad. A.I. Nesterov’s Therapy Department Russian Federation

N. M. Shvyreva

Russian State Medical University, Ministry of Health and Social Development of Russia

Acad. A.I. Nesterov’s Therapy Department Russian Federation

V. A. Egorova

Russian State Medical University, Ministry of Health and Social Development of Russia

Acad. A.I. Nesterov’s Therapy Department Russian Federation

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