THE ROLE OF CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME AFTER THE EMERGENCE OF MORE POWERFUL INHIBITORS OF P2Y12 RECEPTOR

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Abstract

The role of P2Y12 receptor blocker clopidogrel after the introduction into clinical practice of new, more powerful and stable operating drugs belonging to this class of antiplatelet agents is discussed. The advantages and disadvantages of each of the currently used antiplatelet drugs that block the receptor P2Y12 are reviewed. On the basis of the analysis concludes that, despite the emergence of new antiplatelet agents clopidogrel, appears to be widely used for a long time in the treatment of patients with acute coronary syndrome and / or after coronary stenting. This is primarily due to the presence of large evidence base, and confirmation of safety of long-term therapy clopidogrel.

About the authors

S. R. Gilyarevsky

Emergency Care Scientific-Research Institute named N.V. Sklifosovsky

Author for correspondence.
Email: sgilarevsky@rambler.ru
Russian Federation

A. G. Larin

Emergency Care Scientific-Research Institute named N.V. Sklifosovsky

Russian Federation

P. Y. Lopotovsky

Emergency Care Scientific-Research Institute named N.V. Sklifosovsky

Russian Federation

I. M. Kuzmina

Emergency Care Scientific-Research Institute named N.V. Sklifosovsky

Russian Federation

O. V. Baturina

Emergency Care Scientific-Research Institute named N.V. Sklifosovsky

Russian Federation

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Copyright (c) 2011 Gilyarevsky S.R., Larin A.G., Lopotovsky P.Y., Kuzmina I.M., Baturina O.V.

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